480-20-6 Usage
Description
Dihydrokaempferol is a flavonoid compound that possesses antioxidant, cytotoxic, and neuroprotective properties. It is derived from various plant sources and has been found to exhibit potential health benefits due to its bioactive properties.
Uses
Used in Pharmaceutical Industry:
Dihydrokaempferol is used as a therapeutic agent for its antioxidant and cytotoxic effects. It has potential applications in the treatment of various diseases, including cancer, due to its ability to modulate cellular signaling pathways and inhibit tumor growth.
Used in Cosmetic Industry:
Dihydrokaempferol is used as an active ingredient in cosmetics for its antioxidant properties. It helps protect the skin from oxidative stress and may contribute to anti-aging effects.
Used in Nutraceutical Industry:
Dihydrokaempferol is used as a supplement in the nutraceutical industry due to its potential health benefits, including its antioxidant and neuroprotective properties. It may help support cognitive function and overall health.
Used in Research:
Dihydrokaempferol is used as a research compound for studying its potential anti-cholinesterase activity and β-site amyloid precursor protein cleaving enzyme 1 inhibitory properties. These characteristics make it a promising candidate for the development of new drugs targeting neurodegenerative diseases such as Alzheimer's.
Check Digit Verification of cas no
The CAS Registry Mumber 480-20-6 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 0 respectively; the second part has 2 digits, 2 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 480-20:
(5*4)+(4*8)+(3*0)+(2*2)+(1*0)=56
56 % 10 = 6
So 480-20-6 is a valid CAS Registry Number.
InChI:InChI=1/C15H12O6/c16-8-3-1-7(2-4-8)15-14(20)13(19)12-10(18)5-9(17)6-11(12)21-15/h1-6,14-18,20H
480-20-6Relevant articles and documents
Development and Optimization of an in Vitro Multienzyme Synthetic System for Production of Kaempferol from Naringenin
Zhang, Zhiping,He, Yanzhi,Huang, Yue,Ding, Li,Chen, Lei,Liu, Yaxian,Nie, Yesen,Zhang, Xinyue
, p. 8272 - 8279 (2018/07/30)
An in vitro multienzyme synthetic system was developed and optimized to efficiently produce kaempferol in a single reaction tube. Two key genes, Atf3h and Atfls1, in the biosynthetic pathway of kaempferol were cloned into a prokaryotic expression vector and overexpressed in Escherichia coli. The recombinant proteins were purified through affinity chromatography and showed activities of flavanone 3-hydroxylase and flavonol synthase, respectively, followed by development of an in vitro synthetic system for producing kaempferol. The system contains 8.2 mM α-ketoglutaric acid, 0.01 mM ferrous ion, 0.4% sodium ascorbate, 25 μg/mL of each recombinant enzyme, and 10% glycerol in 100 mM Tris-HCl (pH 7.2). When the reaction was carried out at 40 °C for 40-50 min, the yield of kaempferol was 37.55 ± 1.62 mg/L and the conversion rate from NRN to KMF was 55.89% ± 2.74%. Overall, this system provides a promising and efficient approach to produce kaempferol economically.
Heterocycles. XXII. Stereoselective Synthesis of (+)-Aromadendrin Trimethyl Ether and Its Enantiomer, and Their Reduction
Takahashi, Hiroshi,Li, Shaoshun,Harigaya, Yoshihiro,Onda, Masayuki
, p. 1877 - 1881 (2007/10/02)
Two enantiomeric chalcone epoxides 2a and 2b are synthesized under phase-transfer conditions using 1-benzylquinidinium chloride and 1-benzylquininium chloride as catalysts, respectively.Stereoselective cyclisation of 2a and 2b, followed by methylation and