480453-78-9

Basic information

• Product Name: Imidazo[1,2-a]pyridine-7-methanol, 2-(4-fluorophenyl)-3-[2-(methylthio)-4-pyrimidinyl]-
• CAS NO: 480453-78-9
• Molecular Formula: C19H15FN4OS
• Molecular Weight: 366.419
• Mol File: 480453-78-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Imidazo[1,2-a]pyridine-7-methanol, 2-(4-fluorophenyl)-3-[2-(methylthio)-4-pyrimidinyl]-(CAS DataBase Reference)
• NIST Chemistry Reference: Imidazo[1,2-a]pyridine-7-methanol, 2-(4-fluorophenyl)-3-[2-(methylthio)-4-pyrimidinyl]-(480453-78-9)
• EPA Substance Registry System: Imidazo[1,2-a]pyridine-7-methanol, 2-(4-fluorophenyl)-3-[2-(methylthio)-4-pyrimidinyl]-(480453-78-9)

Safety Data

• Hazardous Substances Data: 480453-78-9(Hazardous Substances Data)

Upstream product

• 105250-17-7 2-amino-4-hydroxymethylpyridine 
• 266358-16-1 2-bromo-1-(4-fluorophenyl)-2-(2-methylsulfanylpyrimidin-4-yl)ethanone 
• 695-34-1 2-Amino-4-methylpyridine 
• 14001-63-9 2-methylthio-4-methylpyrimidine 
• 5327-32-2 2-acetylamino-4-methylpyridine 
• 13362-30-6 2-amino-4-ethoxycarbonyl-pyridine 
• 403-33-8 methyl 4-flurobenzoate 
• 54221-95-3 2-(acetylamino)isonicotinic acid 
• 217661-99-9 1-(4-fluorophenyl)-2-(2-methylsulphanylpyrimidin-4-yl)-1-ethanone 

Downstream Products

• 480457-97-4 [2-(4-fluorophenyl)-3-(2-methanesulfonylpyrimidin-4-yl)imidazo[1,2-a]pyridin-7-yl]methanol 
• 762173-03-5 2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyridine-7-carbaldehyde 
• 480458-37-5 [2-(4-fluorophenyl)-3-(2-methanesulfonylpyrimidin-4-yl)imidazo[1,2-a]pyridin-7-ylmethyl]dimethylamine 
• 887645-49-0 [2-(4-fluorophenyl)-3-(2-methylsulfanylpyrimidin-4-yl)imidazo[1,2-a]pyridin-7-ylmethyl]dimethylamine 
• 918955-30-3 methanesulfonic acid 2-(4-fluoro-phenyl)-3-[2-(1-phenyl-ethylamino)-pyrimidin-4-yl]-imidazo[1,2-a]pyridin-7-ylmethyl ester 
• 918955-31-4 methanesulfonic acid 2-(4-fluoro-phenyl)-3-[2-(1-phenyl-ethylamino)-pyrimidin-4-yl]-imidazo[1,2-a]pyridin-7-ylmethyl ester 
• 918955-32-5 methanesulfonic acid 3-[2-(benzyl-methyl-amino)-pyrimidin-4-yl]-2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridin-7-ylmethyl ester 
• 918955-27-8 methanesulfonic acid 3-(2-benzylamino-pyrimidin-4-yl)-2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridin-7-ylmethyl ester 
• 918955-33-6 methanesulfonic acid 3-(2-benzyloxy-pyrimidin-4-yl)-2-(4-fluoro-phenyl)-imidazo[1,2-a]pyridin-7-ylmethyl ester 
• 918955-26-7 [2-(4-fluoro-phenyl)-3-(2-methoxy-pyrimidin-4-yl)-imidazo[1,2-a]pyridin-7-yl]-methanol 

Relevant articles and documents

Synthesis and biological activity of imidazopyridine anticoccidial agents: Part I

Coccidiosis is the major cause of morbidity and mortality in the poultry industry. Protozoan parasites of the genus Eimeria invade the intestinal lining of the avian host causing tissue pathology, poor weight gain, and in some cases mortality. Resistance

Synthesis and SAR of 2-(4-fluorophenyl)-3-pyrimidin-4-ylimidazo[1,2-a]pyridine derivatives as anticoccidial agents

Compounds 10a-10d and 10i are very potent inhibitors of Eimeria tenella cGMP-dependent protein kinase (0.081-0.32 nM) and are very efficacious antiparasitic agents in vivo when administered to chickens at 12.5-25 ppm levels in the feed.