480993-88-2Relevant articles and documents
1,3-Dialkyl-8-N-substituted benzyloxycarbonylamino-9-deazaxanthines as potent adenosine receptor ligands: Design, synthesis, structure-affinity and structure-selectivity relationships
Fernandez, Franco,Caamano, Olga,Isabel Nieto,Lopez, Carmen,Garcia-Mera, Xerardo,Stefanachi, Angela,Nicolotti, Orazio,Isabel Loza,Brea, Jose,Esteve, Cristina,Segarra, Victor,Vidal, Bernat,Carotti, Angelo
experimental part, p. 3618 - 3629 (2009/09/30)
A number of 1,3-dialkyl-9-deazaxanthines (9-dAXs), bearing a variety of N-substituted benzyloxycarbonylamino substituents at position 8, were prepared and evaluated for their binding affinity to the recombinant human adenosine receptors (hARs), chiefly to