480996-91-6

Basic information

• Product Name: methyl 5-methoxy-3-methyl-1H-indole-2-carboxylate
• Synonyms: methyl 5-methoxy-3-methyl-1H-indole-2-carboxylate
• CAS NO: 480996-91-6
• Molecular Formula: C12H13NO3
• Molecular Weight: 219.24
• Mol File: 480996-91-6.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: methyl 5-methoxy-3-methyl-1H-indole-2-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl 5-methoxy-3-methyl-1H-indole-2-carboxylate(480996-91-6)
• EPA Substance Registry System: methyl 5-methoxy-3-methyl-1H-indole-2-carboxylate(480996-91-6)

Safety Data

• Hazardous Substances Data: 480996-91-6(Hazardous Substances Data)

Upstream product

• 480996-78-9 methyl 1-(2-ethoxycarbonylethyl)-5-methoxy-3-methylindole-2-carboxylate 
• 480996-89-2 methyl 1-(2-benzylsulfonylethyl)-5-methoxy-3-methylindole-2-carboxylate 
• 63767-58-8 ethyl 3?((4?methoxyphenyl)amino)propanoate 
• 104-94-9 4-methoxy-aniline 
• 480996-74-5 2-[(2-ethoxycarbonyl-ethyl)-(4-methoxy-phenyl)-amino]-3-oxo-butyric acid methyl ester 
• 1601465-90-0 methyl 2-(2-(4-methoxyphenyl)hydrazono)butanoate 
• 51756-08-2 methyl 2-ethyl-3-oxobutanoate 
• 67-56-1 methanol 
• 21987-25-7 5-methoxy-3-methyl-1H-indole 
• 558-13-4 carbon tetrabromide 
• 95239-02-4 C₁₀H₁₆N₂O₄ 

Relevant articles and documents

Metal and Oxidant Free Construction of Substituted- and/or Polycyclic Indoles: A Useful Alternative to Bischler and Related Syntheses

A wide range of substituted indoles or polycyclic derivatives containing the indole core are easily accessible by acidic treatment of aromatic amines and 1,2-diaza-1,3-dienes. Unlike the related indole-Bischler synthesis, the regioselectivity of the method here reported is unique and predictable, the yields are generally good and also electron withdrawing substituted indoles are smoothly recovered.

Bexarotene prodrugs: Targeting through cleavage by NQO1 (DT-diaphorase)

Bexarotene, a retinoid X receptor (RXR) agonist, is being tested as a potential disease modifying treatment for neurodegenerative conditions. To limit the peripheral exposure of bexarotene and release it only in the affected areas of the brain, we designe