481-59-4

Basic information

• Product Name: Benzeneacetic acid, alpha-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene )-2-methoxy-, methyl ester
• Synonyms: Benzeneacetic acid, alpha-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene )-2-methoxy-, methyl ester;Leprapic acid;Leprapinic acid;α-[(2E)-3-Hydroxy-5-oxo-4-phenyl-2,5-dihydrofuran-2-ylidene]-2-methoxybenzeneacetic acid methyl ester
• CAS NO: 481-59-4
• Molecular Formula: C₂₀H₁₆O₆
• Molecular Weight: 352.34
• Mol File: 481-59-4.mol
• Article Data: 4

Chemical Properties

• Appearance: /
• CAS DataBase Reference: Benzeneacetic acid, alpha-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene )-2-methoxy-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Benzeneacetic acid, alpha-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene )-2-methoxy-, methyl ester(481-59-4)
• EPA Substance Registry System: Benzeneacetic acid, alpha-(3-hydroxy-5-oxo-4-phenyl-2(5H)-furanylidene )-2-methoxy-, methyl ester(481-59-4)

Safety Data

• Hazardous Substances Data: 481-59-4(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 6273-79-6 Pulvinic acid lacton 
• 186581-53-3 diazomethane 
• 93796-43-1 2'-methoxypulvinic acid 
• 6200-02-8 (3-methoxy-5-oxo-4-phenyl-5H-furan-2-ylidene)-(2-methoxy-phenyl)-acetic acid methyl ester 
• 866556-32-3 4-methoxy-2-(2-methoxy-phenyl)-3-oxo-butyric acid methyl ester 
• 866556-33-4 (Z)-4-Methoxy-2-(2-methoxy-phenyl)-3-trimethylsilanyloxy-but-2-enoic acid methyl ester 
• 866556-34-5 1-Methoxy-2-{(Z)-3-methoxy-1-[1-methoxy-1-trimethylsilanyloxy-meth-(Z)-ylidene]-2-trimethylsilanyloxy-allyl}-benzene 
• 27798-60-3 methyl 2-(2-methoxyphenyl)acetate 
• 114590-96-4 pulvinic acid 

Relevant articles and documents

Synthesis of leprapinic acid, calycine and analogues by sequential "[3+2] cyclization/suzuki/lactonization" reactions

Calycine and analogues were prepared on the basis of Suzuki cross-coupling reactions of γ-alkylidene-α-hydroxybutenolides - readily available by cyclization of 1,3-dicarbonyl dianions or 1,3-bis(silyl enol ether)s with oxalyl derivatives - and subsequent boron tribromide-mediated lactonization. Leprapinic acid was prepared by chemoselective boron tribromide-mediated deprotection of permethylated leprapinic acid. Wiley-VCH Verlag GmbH & Co. KGaA, 2005.

ONE POT ONE STEP PHOTOCONVERSION OF PULVINIC ACID DILASCTONE TO p-METHOXYVULPINIC ACID

The utility of singlet oxygen-methanol as a reagent for nuclear methoxylation of complex organic natural products is illustrated by a one pot one step photoconversion of pulvinic acid dilactone to p-methoxyvulpinic acid.The study is important from biogenetic considerations.