482-59-7

Basic information

• Product Name: 1,2,3,4,4a,4b,5,6,7,8,8b,9,10,11,12,12b-Hexadecahydro-1,8a,12a-triazatriphenylene
• Synonyms: 1,2,3,4,4a,4b,5,6,7,8,8b,9,10,11,12,12b-Hexadecahydro-1,8a,12a-triazatriphenylene;Isotripiperideine;Tetradecahydro-2H,11H-tripyrido[1,2-a:1',2'-c:3'',2''-e]pyrimidine
• CAS NO: 482-59-7
• Molecular Formula: C₁₅H₂₇N₃
• Molecular Weight: 249.4
• Mol File: 482-59-7.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1,2,3,4,4a,4b,5,6,7,8,8b,9,10,11,12,12b-Hexadecahydro-1,8a,12a-triazatriphenylene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2,3,4,4a,4b,5,6,7,8,8b,9,10,11,12,12b-Hexadecahydro-1,8a,12a-triazatriphenylene(482-59-7)
• EPA Substance Registry System: 1,2,3,4,4a,4b,5,6,7,8,8b,9,10,11,12,12b-Hexadecahydro-1,8a,12a-triazatriphenylene(482-59-7)

Safety Data

• Hazardous Substances Data: 482-59-7(Hazardous Substances Data)

Upstream product

• 110-89-4 piperidine 
• 2156-71-0 N-chloropiperidine 
• 16978-76-0 (E)-1-(phenyldiazenyl)piperidine 
• 873967-85-2 N-(1-acetyl-[2]piperidyl)-acetamide 
• 96-41-3 Cyclopentanol 
• 522-33-8 α-tripiperideine 
• 522-33-8 Tripiperidin 
• 111-30-8 Glutaraldehyde 
• 504-29-0 2-aminopyridine 
• 5231-96-9 N-(2-pyridyl)acetamide 

Downstream Products

• 505-18-0 2,3,4,5-tetrahydropyridine 
• 20824-32-2 Ammodendrin 
• 108039-40-3 optically inactive 1r,3t-bis-((4ar,4bt,9at,14at)-dodecahydro-tripyrido[1,2-a;1',2'-c;3'',2''-e]pyrimidine-1-carbonyl)-2c,4t-diphenyl-cyclobutane 
• 47077-87-2 N-Benzoyl-Δ²-tetrahydroanabasin 
• 14483-24-0 2,3-tetramethylene-1,2-dihydroquinazolinium picrate 
• 108040-95-5 (+/-)-1-trans-cinnamoyl-(4ar,4bt,9at,14at)-tetradecahydro-tripyrido[1,2-a;1',2'-c;3'',2''-e]pyrimidine 
• 100660-03-5 1,2,3,4,5,6,3',4',5',6'-decahydro-[2,3']bipyridyl; dipicrate trihydrate 
• 5174-66-3 1,2,3,4,5,6,3',4',5',6'-decahydro-[2,3']bipyridinyl 
• 110-89-4 piperidine 
• 46041-04-7 dodecahydro-[2,3']bipyridinyl 
• 2467-09-6 (2RS,3'SR)-Dodecahydro-[2,3']bipyridyl 
• 2446-62-0 7,8,9-trihydropyrido[2,1-b]quinazolin-11(6H)-one 

Relevant articles and documents

Dynamic Covalent Metathesis in the C=C/C=N Exchange between Knoevenagel Compounds and Imines

Fast and reversible dynamic covalent C=C/C=N exchange takes place without catalyst in nonpolar solvents between barbiturate-derived Knoevenagel (Kn) compounds and imines. A detailed study of the reaction indicates that it proceeds by an associative organo-metathesis mechanism involving the formation of a four-membered ring azetidine intermediate by addition of the imine C=N group to the C=C bond of the Kn compound. This intermediate could be generated cleanly and stabilized at low temperature by condensation of the o,p-dinitrophenyl Kn derivative with the cyclic imine 1-azacyclohexene. It was characterized by extensive NMR and mass spectrometric studies. The process described represents a genuine dynamic covalent organo-metathesis through a four-membered ring adduct as intermediate. It paves the way for the exploration of a wide set of dynamic systems involving (strongly) polarized C=C bonds and various imines, extending also into covalent dynamic polymers and polymolecular assemblies.