482374-63-0

Basic information

• Product Name: 2H-1-Benzopyran-3-carboxylic acid, 7-chloro-, ethyl ester
• CAS NO: 482374-63-0
• Molecular Formula: C12H11ClO3
• Molecular Weight: 238.671
• Mol File: 482374-63-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 2H-1-Benzopyran-3-carboxylic acid, 7-chloro-, ethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2H-1-Benzopyran-3-carboxylic acid, 7-chloro-, ethyl ester(482374-63-0)
• EPA Substance Registry System: 2H-1-Benzopyran-3-carboxylic acid, 7-chloro-, ethyl ester(482374-63-0)

Safety Data

• Hazardous Substances Data: 482374-63-0(Hazardous Substances Data)

Upstream product

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Relevant articles and documents

Design, synthesis, and SAR of cis-1,2-diaminocyclohexane derivatives as potent factor Xa inhibitors. Part II: Exploration of 6-6 fused rings as alternative S1 moieties

A series of cis-1,2-diaminocyclohexane derivatives possessing a 6-6 fused ring for the S1 moiety were synthesized as novel factor Xa (fXa) inhibitors. The synthesis, structure-activity relationship (SAR), and physicochemical properties are reported herein, together with the discovery of compound 45c, which has potent anti-fXa activity, good physicochemical properties and pharmacokinetic (PK) profiles, including a reduced negative food effect.