483-10-3 Usage
Description
Corynanthe, also known as Corynantheine, is an alkaloid derived from the bark of Rauwolfia serpentina. It is characterized by its colorless crystalline structure and exhibits a specific optical rotation of [α]20D 82° (c 0.5, pyridine). CORYNANTHINE has been extensively studied for its potential applications in various fields.
Uses
Used in Pharmaceutical Industry:
Corynantheine is used as a pharmaceutical compound for its potential therapeutic effects. It has been found to possess various bioactive properties, making it a promising candidate for the development of new drugs and treatments.
Used in Traditional Medicine:
Corynantheine has been traditionally used in traditional medicine, particularly in the treatment of various ailments and conditions. Its alkaloid nature and bioactive properties contribute to its effectiveness in this application.
Used in Research and Development:
Due to its unique chemical structure and properties, Corynantheine is used as a research compound for the development of new drugs and therapies. Its potential applications in various fields make it an important compound for further investigation and development.
References
Hoffmann., Helv. Chim. Acta, 37,314,849 (1954)
Check Digit Verification of cas no
The CAS Registry Mumber 483-10-3 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 3 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 483-10:
(5*4)+(4*8)+(3*3)+(2*1)+(1*0)=63
63 % 10 = 3
So 483-10-3 is a valid CAS Registry Number.
InChI:InChI=1/C21H26N2O3/c1-26-21(25)19-15-10-17-20-14(13-4-2-3-5-16(13)22-20)8-9-23(17)11-12(15)6-7-18(19)24/h2-5,12,15,17-19,22,24H,6-11H2,1H3/t12-,15-,17-,18-,19-/m0/s1
483-10-3Relevant articles and documents
Total Syntheses of Yohimbe Alkaloids, with Stereoselection for the Normal, Allo, and 3-Epiallo Series, Based on Annelations of 4-Methoxy-1,2-dihydropyridones
Kuehne, Martin E.,Muth, Randy S.
, p. 2701 - 2712 (2007/10/02)
N--2,3-dihydro-4-pyridone (31) was generated in two steps (77percent yield) from tryptamine and N-methyl-4-piperidone methiodide.Its cyclization (90percent yield) and oxidation (91percent yield) provided the tetracyclic analogue 32.O-Methylation and Robinson-type annelation of these vinylogous lactams (the latter in form of its Na-carbamate) furnished the dienones 38 (64percent) and 43 (90percent).Further elaboration by cyclization and/or reduction reactions selectively provided the 15,16-didehydroyohimbinones 7 and 44.Their reductions then led to yohimbinone (52, 20percent overall yield from tryptamine), alloyohimbinone (11, 19percent overall yield), and 3-epi-alloyohimbinone (10, 23percent overall yield), which led to yohimbine (3), β-yohimbine (9), 3-epi-alloyohimbine (53), and 3-epi-17-epi-alloyohimbine (54).
Total synthesis of yohimbine.
van Tamelen,Shamma,Burgstahler,Wolinsky,Tamm,Aldrich
, p. 7315 - 7333 (2007/10/04)
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