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483-17-0

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  • 6-Isoquinolinol,1-[[(2S,3R,11bS)-3-ethyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl]methyl]-1,2,3,4-tetrahydro-7-methoxy-,(1R)-

    Cas No: 483-17-0

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483-17-0 Usage

Description

Cephaeline is a pyridoisoquinoline alkaloid with a hydroxy group at the 6'-position and methoxy substituents at the 7'-, 10-, and 11-positions. It is a crystalline solid that can be found in the ground roots of ipecac, along with emetine. The Brazilian variety of ipecac typically contains about 0.5% cephaeline.

Uses

Used in Pharmaceutical Applications:
Cephaeline is used as an emetic, which is a substance that induces vomiting, and as an anti-amebic reagent, which is a substance used to detect or counteract the presence of amoebae in the body. Its emetic properties make it useful in certain medical treatments where vomiting is necessary, while its anti-amebic properties help in the treatment of infections caused by amoebae.
Used in the Pharmaceutical Industry:
Cephaeline is used as an active pharmaceutical ingredient for the development of medications that target various health conditions. Its emetic and anti-amebic properties contribute to its use in the formulation of drugs aimed at treating specific illnesses and infections.

Health Hazard

The toxicity of cephaeline is lower than thatof emetine. The toxic effects are cumula tive. Ingestion of high doses may producehypotension, muscle weakness, and gastroin testinal problems, including nausea, vomiting, and diarrhea.

Check Digit Verification of cas no

The CAS Registry Mumber 483-17-0 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 4,8 and 3 respectively; the second part has 2 digits, 1 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 483-17:
(5*4)+(4*8)+(3*3)+(2*1)+(1*7)=70
70 % 10 = 0
So 483-17-0 is a valid CAS Registry Number.
InChI:InChI=1/C28H38N2O4/c1-5-17-16-30-9-7-19-13-27(33-3)28(34-4)15-22(19)24(30)11-20(17)10-23-21-14-26(32-2)25(31)12-18(21)6-8-29-23/h12-15,17,20,23-24,29,31H,5-11,16H2,1-4H3/t17-,20-,23+,24-/m0/s1

483-17-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 20, 2017

Revision Date: Aug 20, 2017

1.Identification

1.1 GHS Product identifier

Product name cephaeline

1.2 Other means of identification

Product number -
Other names Emetan-6‘-ol, 7‘,10,11-trimethoxy-

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:483-17-0 SDS

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