484638-53-1

Basic information

• Product Name: (R)-3-[1-(4-bromo-benzyl)-5-methoxy-2-methyl-1H-indol-3-yl]-butanal
• Synonyms: (R)-3-[1-(4-bromo-benzyl)-5-methoxy-2-methyl-1H-indol-3-yl]-butanal
• CAS NO: 484638-53-1
• Molecular Weight: 400.315
• Mol File: 484638-53-1.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: (R)-3-[1-(4-bromo-benzyl)-5-methoxy-2-methyl-1H-indol-3-yl]-butanal(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-3-[1-(4-bromo-benzyl)-5-methoxy-2-methyl-1H-indol-3-yl]-butanal(484638-53-1)
• EPA Substance Registry System: (R)-3-[1-(4-bromo-benzyl)-5-methoxy-2-methyl-1H-indol-3-yl]-butanal(484638-53-1)

Safety Data

• Hazardous Substances Data: 484638-53-1(Hazardous Substances Data)

Upstream product

• 123-73-9 trans-Crotonaldehyde 
• 79-43-6 dichloro-acetic acid 
• 346440-54-8 (2S,5S)-5-benzyl-2-(tert-butyl)-3-methylimidazolidin-4-one 

Relevant articles and documents

Enantioselective transformation of alpha, beta-unsaturated aldehydes using chiral organic catalysts

Nonmetallic organic catalysts are provided that facilitate the enantioselective reaction of α,β-unsaturated aldehydes. The catalysts are chiral imidazolidinone compounds having the structure of formula (IIA) or (IIB) or are acid addition salts thereof, wherein, in one preferred embodiment, R1 is C1-C6 alkyl, R2 is tri(C1-C6 alkyl)-substituted methyl, R3 and R4 are hydrogen, and R5 is phenyl optionally substituted with 1 or 2 substituents selected from the group consisting of halo, hydroxyl, and C1-C6 alkyl. The chiral imidazolidinones are useful in catalyzing a wide variety of reactions, including cycloaddition reactions, Friedel-Crafts alkylation reactions, and Michael additions.