486393-38-8

Basic information

• Product Name: 1-Piperazinebutanenitrile, 4-(2,3-dichlorophenyl)-
• CAS NO: 486393-38-8
• Molecular Formula: C14H17Cl2N3
• Molecular Weight: 298.215
• Mol File: 486393-38-8.mol
• Article Data: 8

Chemical Properties

• CAS DataBase Reference: 1-Piperazinebutanenitrile, 4-(2,3-dichlorophenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Piperazinebutanenitrile, 4-(2,3-dichlorophenyl)-(486393-38-8)
• EPA Substance Registry System: 1-Piperazinebutanenitrile, 4-(2,3-dichlorophenyl)-(486393-38-8)

Safety Data

• Hazardous Substances Data: 486393-38-8(Hazardous Substances Data)

Upstream product

• 41202-77-1 1-(2,3-dichlorophenyl)piperazine 
• 5332-06-9 4-bromobutanenitrile 

Downstream Products

• 869383-25-5 6-chloro-N-{4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-nicotinamide 
• 189061-44-7 4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butylamine 
• 644988-73-8 5-bromo-benzo[b]thiophene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide 
• 644988-83-0 5-bromo-benzofuran-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide 
• 744213-74-9 5-bromo-thiophene-2-carboxylic acid {4-[4-(2,3-dichloro-phenyl)-piperazin-1-yl]-butyl}-amide 

Relevant articles and documents

Conformationally-flexible benzamide analogues as dopamine D3 and σ2 receptor ligands

A series of conformationally-flexible analogues was prepared and their affinities for D2-like dopamine (D2, D3 and D 4) were determined using in vitro radioligand binding assays. The results of this structure-activity rela

Synthesis and evaluation of amides surrogates of dopamine D3 receptor ligands

Isosteric replacement of the amide function and modulation of the arylpiperazine moiety of known dopamine D3 receptor ligands led to potent and selective compounds. Enhanced bioavailability and preferential brain distribution make compound 6c a good candi

Synthesis and in vitro binding of N-phenyl piperazine analogs as potential dopamine D3 receptor ligands

The synthesis of a series of N-(2-methoxyphenyl)piperazine and N-(2,3-dichlorophenyl)piperazine analogs and their in vitro binding affinities for dopamine D2, D3, D4 are presented. A series of N-(2-methoxyphenyl)piperazine