4866-85-7

Basic information

• Product Name: 1-(hydroxymethyl)-4-(2-hydroxyethyl)benzene
• Synonyms: 1-(hydroxymethyl)-4-(2-hydroxyethyl)benzene
• CAS NO: 4866-85-7
• Molecular Weight: 152.193
• Mol File: 4866-85-7.mol
• Article Data: 7

Chemical Properties

• Melting Point: 30 °C (approx)
• Boiling Point: 140-145 °C(Press: 23 Torr)
• Density: 1.139±0.06 g/cm3(Predicted)
• CAS DataBase Reference: 1-(hydroxymethyl)-4-(2-hydroxyethyl)benzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(hydroxymethyl)-4-(2-hydroxyethyl)benzene(4866-85-7)
• EPA Substance Registry System: 1-(hydroxymethyl)-4-(2-hydroxyethyl)benzene(4866-85-7)

Safety Data

• Hazardous Substances Data: 4866-85-7(Hazardous Substances Data)

Usage

Type of compound

Phenolic compound

Structure

Contains a phenol group, a benzene ring, and two hydroxyl groups attached to the benzene ring

Uses

a. Intermediate in the synthesis of various organic compounds
b. Pharmaceutical industry
c. Dyes manufacturing
d. Polymer production
e. Industrial products
f. Fragrance ingredient
g. Perfumes and personal care products production

Upstream product

• 52787-14-1 methyl 4-(2-methoxy-2-oxoethyl)benzoate 
• 501-89-3 4-(carboxymethyl)benzoic acid 

Downstream Products

• 79050-33-2 4-(2-bromoethyl)-1-(bromomethyl)benzene 
• 163164-47-4 4-mono(2-hydroxyethyl)benzaldehyde 

Relevant articles and documents

Photoredox-Catalyzed Synthesis of α-Amino Acid Amides by Imine Carbamoylation

An operationally simple protocol for the photocatalytic carbamoylation of imines is reported. Easily available, bench-stable 4-amido Hantzsch ester derivatives serve as precursors to carbamoyl radicals that undergo rapid addition to N-aryl imines. The reaction proceeds under blue light irradiation in the presence of the photocatalyst 3DPAFIPN and Br?nsted/Lewis acid additives. Mechanistic studies indicated a photoredox mechanism that involves carbamoyl radicals.

ETHER COMPOUNDS AND USES THEREOF

The present invention provides compounds that modulate protein function, to restore protein homeostasis and/or cell-cell adhesion. The invention provides methods of modulating protein-mediated diseases, such as cytokine-mediated diseases, disorders, conditions, or responses. Compositions of these compounds are also provided. Methods of treatment, amelioration, or prevention of protein-mediated diseases, disorders, and conditions are also provided.

Paracyclophanes: Extending the bridges. Synthesis

Preparatively satisfactory routes to [3.2]paracyclophane (10), [4.2]paracyclophane (14), [4.3]paracyclophane (19) as well as several derivatives of these compounds - among others the bromides 25, the ester 31, the diesters 40-43 - are described using well-established methods of cyclophane chemistry (ring-closure reactions leading to thiacyclophanes, ring contraction by sulfone pyrolysis). The parent systems and their derivatives are now available in gram quantities allowing a study of their chemical properties. Wiley-VCH Verlag GmbH & Co. KGaA, 2009.