487040-99-3Relevant articles and documents
Antibacterial oxazolidinones possessing a novel C-5 side chain. (5R)-trans-3-[3-fluoro-4-(1-oxotetrahydrothiopyran-4-yl)phenyl] -2-oxooxazolidine-5-carboxylic acid amide (PF-00422602), a new lead compound
Poel, Toni-Jo,Thomas, Richard C.,Adams, Wade J.,Aristoff, Paul A.,Barbachyn, Michael R.,Boyer, Frederick E.,Brieland, Joan,Brideau, Roger,Brodfuehrer, Joanne,Brown, Alan P.,Choy, Allison L.,Dermyer, Michael,Dority, Michael,Ford, Charles W.,Gadwood, Robert C.,Hanna, Debra,Hongliang, Cai,Huband, Michael D.,Huber, Christopher,Kelly, Rose,Kim, Ji-Young,Martin Jr., Joseph P.,Pagano, Paul J.,Ross, Daniel,Skerlos, Laura,Sulavik, Mark C.,Zhu, Tong,Zurenko, Gary E.,Vara Prasad
, p. 5886 - 5889 (2007)
Oxazolidinones possessing a C-5 carboxamide functionality (reverse amides) represent a new series of compounds that block bacterial protein synthesis. These reverse amides also exhibited less potency against monoamine oxidase (MAO) enzymes and thus posses
N-aryl-2-oxazolidinone-5-carboxamides and their derivatives
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Page 41, (2010/02/07)
The present invention provides antibacterial agents having the formulae I, II, and III described herein.
