4873-37-4Relevant articles and documents
Identification of a new class of small molecule C5a receptor antagonists
Chen, Jack J.,Cole, Derek C.,Ciszewski, Greg,Crouse, Kimberly,Ellingboe, John W.,Nowak, Pawel,Tawa, Gregory J.,Berstein, Gabriel,Li, Wei
scheme or table, p. 662 - 664 (2010/06/21)
C5a is a terminal product of the complement cascade that activates and attracts inflammatory cells including granulocytes, mast cells and macrophages via a specific GPCR, the C5a receptor (C5aR). Inhibition of C5a/C5aR interaction has been shown to be eff