488-87-9

Basic information

• Product Name: 2,5-DIMETHYLRESORCINOL
• Synonyms: 1,3-Benzenediol, 2,5-dimethyl-;Betorcinol;2,5-DIMETHYLRESORCINOL 99%;2,5-Dimethyl-1,3-benzenediol;2,5-Dimethylbenzene-1,3-diol;2,5-Dimethylresorcinol,99%;1,3-Dihydroxy-2,5-dimethylbenzene p-Xylene-2,6-diol;2,5-DIMETHYLRESORCINOL FOR SYNTHESIS
• CAS NO: 488-87-9
• Molecular Formula: C₈H₁₀O₂
• Molecular Weight: 138.16
• EINECS: 207-688-3
• Product Categories: Aromatic Hydrocarbons (substituted) & Derivatives;Alcohols;Monomers;Polymer Science
• Mol File: 488-87-9.mol
• Article Data: 5

Chemical Properties

• Melting Point: 157-162 °C(lit.)
• Boiling Point: 277 °C(lit.)
• Flash Point: 140.8 °C
• Appearance: white to tan powder
• Density: 1.0742 (rough estimate)
• Vapor Pressure: 0.00178mmHg at 25°C
• Refractive Index: 1.5231 (estimate)
• Storage Temp.: Store below +30°C.
• PKA: 9.91±0.15(Predicted)
• CAS DataBase Reference: 2,5-DIMETHYLRESORCINOL(CAS DataBase Reference)
• NIST Chemistry Reference: 2,5-DIMETHYLRESORCINOL(488-87-9)
• EPA Substance Registry System: 2,5-DIMETHYLRESORCINOL(488-87-9)

Safety Data

• Hazard Codes: C
• Statements: 20/21/22-34
• Safety Statements: 26-27-28-36/37/39-45
• RIDADR: UN 3261 8/PG 2
• WGK Germany: 3
• HazardClass: 8
• PackingGroup: III
• Hazardous Substances Data: 488-87-9(Hazardous Substances Data)

Usage

Chemical Properties

white to tan powder

InChI:InChI=1/C8H10O2/c1-5-3-7(9)6(2)8(10)4-5/h3-4,9-10H,1-2H3

Upstream product

• 67-56-1 methanol 
• 644-66-6 4-(3-formyl-2-hydroxy-4-methoxy-6-methylbenzoyloxy)-2-hydroxy-3,6-dimethylbenzoic acid 
• 64-17-5 ethanol 
• 17636-16-7 barbatic acid 
• 526-37-4 atranol 
• 57074-21-2 3-chloro-2,6-dihydroxy-4-methylbenzaldehyde 
• 4707-47-5 2,4-dihydroxy-3,6-dimethyl-benzoic acid methyl ester 
• 61621-48-5 4,6-dibromo-2,5-dimethyl-resorcinol 
• 65151-57-7 3-nitro-2,5-dimethylphenol 
• 569-36-8 squamatic Acid 
• 64-19-7 acetic acid 
• 4707-46-4 2,4-dihydroxy-3,6-dimethylbenzoic acid 
• 479-20-9 atranorin 
• 20372-89-8 4-(2,4-dihydroxy-3,6-dimethylbenzoyloxy)-2-hydroxy-3,6-dimethylbenzoic acid 

Downstream Products

• 34883-14-2 2,4-dihydroxy-3,6-dimethylbenzaldehyde 
• 49582-98-1 1,3-diacetoxy-2,5-dimethyl-benzene 
• 61621-48-5 4,6-dibromo-2,5-dimethyl-resorcinol 
• 69082-35-5 1-acetyl-2,4-dihydroxy-3,6-dimethylbenzene 
• 96761-50-1 2-(2,4-dihydroxy-3,6-dimethyl-phenyl)-7-hydroxy-1,4,6,9-tetramethyl-phenoxazin-3-one 
• 95620-71-6 7-amino-8-(2,4-dihydroxy-3,6-dimethyl-phenyl)-1,4,6,9-tetramethyl-phenoxazin-3-one 
• 96675-22-8 7-amino-2,8-bis-(2,4-dihydroxy-3,6-dimethyl-phenyl)-1,4,6,9-tetramethyl-phenoxazin-3-one 
• 105164-70-3 2,5,2',5'-tetramethyl-4,4'-(7-amino-3-imino-1,4,6,9-tetramethyl-3H-phenoxazine-2,8-diyl)-bis-benzene-1,3-diol 
• 105144-69-2 5,5'-dihydroxy-3,6,3',6'-tetramethyl-2,2'-(7-hydroxy-1,4,6,9-tetramethyl-3-oxo-3H-phenoxazine-2,8-diyl)-bis-[1,4]benzoquinone 
• 103864-11-5 2-[7-amino-8-(2,4-dihydroxy-3,6-dimethyl-phenyl)-1,4,6,9-tetramethyl-3-oxo-3H-phenoxazin-2-yl]-5-hydroxy-3,6-dimethyl-[1,4]benzoquinone 
• 116480-12-7 1-nitroso-2,4-dihydroxy-3,6-dimethylbenzene 
• 10493-51-3 4.4'-Dihydroxy-3.6.3'.6'-tetramethyl-biphenyldichinon 
• 97152-10-8 7-acetoxy-8-(2,4-diacetoxy-3,6-dimethyl-phenyl)-1,4,6,9-tetramethyl-phenoxazin-3-one 
• 105841-86-9 5,5'-diacetoxy-3,6,3',6'-tetramethyl-2,2'-(7-acetoxy-1,4,6,9-tetramethyl-3-oxo-3H-phenoxazine-2,8-diyl)-bis-[1,4]benzoquinone 

Relevant articles and documents

Monocyclic Quinone Structure-Activity Patterns: Synthesis of Catalytic Inhibitors of Topoisomerase II with Potent Antiproliferative Activity

The monocyclic 1,4-benzoquinone, HU-331, the direct oxidation product of cannabidiol, inhibits the catalytic activity of topoisomerase II but without inducing DNA strand breaks or generating free radicals, and unlike many fused-ring quinones exhibits minimal cardiotoxicity. Thus, monocyclic quinones have potential as anticancer agents, and investigation of the structural origins of their biological activity is warranted. New syntheses of cannabidiol and (±)-HU-331 are here reported. Integrated synthetic protocols afforded a wide range of polysubstituted resorcinol derivatives; many of the corresponding novel 2-hydroxy-1,4-benzoquinone derivatives are potent inhibitors of the catalytic activity of topoisomerase II, some more so than HU-331, whose monoterpene unit replaced by a 3-cycloalkyl unit conferred increased antiproliferative properties in cell lines with IC50 values extending below 1 mM, and greater stability in solution than HU-331. The principal pharmacophore of quinones related to HU-331 was identified. Selected monocyclic quinones show potential for the development of new anticancer agents.

1 -HYDROXY-BENZOOXABOROLES AS ANTIPARASITIC AGENTS

Provided are compounds useful for controlling endoparasites both in animals and agriculture. Further provided are methods for controlling endoparasite infestations of an animal by administering an effective amount of a compound as described above, or a pharmaceutically acceptable salt thereof, to an animal, as well as formulations for controlling endoparasite infestations using the compounds described above or an acceptable salt thereof, and an acceptable carrier. The claimed compounds are described by the following Markush formula:A typical example for a compound according to above formula is: A typical example for a compound according to above formula is:

Thermal Decomposition of Lichen Depsides

The thermal decomposition of the following lichen depsides has been described: lecanoric acid, gyrophoric acid, evernic acid, perlatolic acid, planaic acid, confluentic acid, atranorin, 4-O-demethylbarbatic acid, and sekikaic acid.Main reaction products are decarboxylated compounds, phenolic units, rearranged depsides, and xanthones.Triethylammonium salts of depside carboxylic acids decompose at reasonably lower temperature than the corresponding free acids. - Keywords: Lichen Depsides, Thermal Decomposition