488829-41-0

Basic information

• Product Name: 5-[1-(1H-Indol-3-yl)-meth-(Z)-ylidene]-2-{[1-phenyl-meth-(E)-ylidene]-hydrazono}-imidazolidin-4-one
• Synonyms: 5-[1-(1H-Indol-3-yl)-meth-(Z)-ylidene]-2-{[1-phenyl-meth-(E)-ylidene]-hydrazono}-imidazolidin-4-one
• CAS NO: 488829-41-0
• Molecular Weight: 329.361
• Mol File: 488829-41-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-[1-(1H-Indol-3-yl)-meth-(Z)-ylidene]-2-{[1-phenyl-meth-(E)-ylidene]-hydrazono}-imidazolidin-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[1-(1H-Indol-3-yl)-meth-(Z)-ylidene]-2-{[1-phenyl-meth-(E)-ylidene]-hydrazono}-imidazolidin-4-one(488829-41-0)
• EPA Substance Registry System: 5-[1-(1H-Indol-3-yl)-meth-(Z)-ylidene]-2-{[1-phenyl-meth-(E)-ylidene]-hydrazono}-imidazolidin-4-one(488829-41-0)

Safety Data

• Hazardous Substances Data: 488829-41-0(Hazardous Substances Data)

Upstream product

• 100-52-7 benzaldehyde 
• 10258-18-1 (5Z)-5-((1H-indol-3-yl)methylene)-2-thioxoimidazolidin-4-one 
• 487-89-8 Indole-3-carboxaldehyde 
• 41097-64-7 (E)-benzaldehyde hydrazone 
• 488829-32-9 5-[1-(1H-Indol-3-yl)-meth-(Z)-ylidene]-2-methylsulfanyl-3,5-dihydro-imidazol-4-one 

Relevant articles and documents

A convenient preparation of 2-(2-arylidene)- and 2-(2-polyhydroxyalkylidene)hydrazono-4-imidazolidinones with various heterocyclic side chain substituents at position 5 as potential antiviral and antitumor agents

A variety of novel 5-[(Z)-arylidene]-2-[(2-(E)-arylidene)hydrazono]4-imidazolidinones 1a-c to 4a,b and 5-[(Z)-arylidene]-2-[(2-(E)-polyhydroxyalkylidene)hydrazono]-4- imidazolidinones 5a-c to 7a-c were prepared from the reaction of 5-[(Z)-arylidene]-2-methylmercaptohydantoins 8a-c with 2-(E)-arylidene hydrazones 13a-d and/or 2-(E)-monosaccharides hydrazones 16a-c. The linear structure, and not that of the angular isomer, has been selected for the products. This structure has been confirmed from a model study of the condensation of 5-[(Z)-2-thienylidene]-2-hydrazono-4-imidazolidinone 9a with benzaldehyde and D-galactose, respectively. The acetylation and benzoylation reactions of compounds 1-7 have been studied. All the new compounds were tested for their potential antiviral and antitumor activities.