4891-18-3

Basic information

• Product Name: (2-methoxy-3,6-dioxabicyclo[3.1.0]hex-4-yl)methanol
• Synonyms: Aids124349;Aids-124349;Methyl 2,3-anhydropentofuranoside;Nsc23609
• CAS NO: 4891-18-3
• Molecular Formula: C₆H₁₀O₄
• Molecular Weight: 146.143
• Mol File: 4891-18-3.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 245.3 °C at 760 mmHg
• Flash Point: 102.2 °C
• Appearance: /
• Density: 1.33 g/cm³
• Vapor Pressure: 0.0048mmHg at 25°C
• Refractive Index: 1.503
• CAS DataBase Reference: (2-methoxy-3,6-dioxabicyclo[3.1.0]hex-4-yl)methanol(CAS DataBase Reference)
• NIST Chemistry Reference: (2-methoxy-3,6-dioxabicyclo[3.1.0]hex-4-yl)methanol(4891-18-3)
• EPA Substance Registry System: (2-methoxy-3,6-dioxabicyclo[3.1.0]hex-4-yl)methanol(4891-18-3)

Safety Data

• Hazardous Substances Data: 4891-18-3(Hazardous Substances Data)

Usage

General Description

(2-methoxy-3,6-dioxabicyclo[3.1.0]hex-4-yl)methanol, also known as p-dioxane, is a chemical compound with a bicyclic structure containing an ether and alcohol functional group. It is commonly used as a solvent, particularly in the production of pharmaceuticals and in synthesis of organic compounds. The compound has a relatively low toxicity and is not considered to be highly hazardous to human health or the environment. However, as with any chemical, proper handling and storage procedures should be followed to minimize any potential risks.

InChI:InChI=1/C6H10O4/c1-8-6-5-4(10-5)3(2-7)9-6/h3-7H,2H2,1H3

Upstream product

• 67-56-1 methanol 
• 124-41-4 sodium methylate 
• 110337-20-7 methyl-[O³-methanesulfonyl-O⁵-methoxycarbonyl-ξ-D-xylofuranoside 
• 109454-69-5 methyl-[O⁵-methoxycarbonyl-O³-(toluene-4-sulfonyl)-ξ-D-xylofuranoside 
• 1824-97-1 methyl β-D-xylofuranoside 
• 79083-42-4 methyl D-arabinofuranoside 
• 58-86-6 D-xylose 

Downstream Products

• 5467-30-1 methyl-(S-ethyl-3-thio-β-D-xylofuranoside) 
• 64623-01-4 methyl-[O⁵-(4-nitro-benzoyl)-2,3-anhydro-β-D-ribofuranoside] 
• 20535-09-5 2,3-Anhydro-5-O-benzyl-β-D-ribofuranoside de methyle 
• 143604-34-6 5-O-Benzyl-3-chloro-2,3-didesoxy-2-dimethylamino-β-D-arabinofuranoside de methyle 
• 143604-33-5 5-O-Benzyl-2-chloro-2,3-didesoxy-3-dimethylamino-β-D-xylofuranoside de methyle 
• 143604-53-9 Methanesulfonate(1R,2S,4R,5S)-2-benzyloxymethyl-4-methoxy-6,6-dimethyl-3-oxa-6-azonia-bicyclo[3.1.0]hexane; 
• 60019-10-5 3-Amino-5-O-benzyl-3-desoxy-β-D-xylofuranoside de methyle 
• 143604-32-4 2-Amino-5-O-benzyl-2-desoxy-β-D-arabinofuranoside de methyle 
• 143604-38-0 5-O-Benzyl-2-desoxy-2-dimethylamino-β-D-arabinofuranoside de methyle 
• 143604-55-1 5-O-Benzyl-2,3-didesoxy-2-dimethylamino-3-fluoro-β-D-arabinofuranoside de methyle 
• 143604-36-8 5-O-Benzyl-3-desoxy-3-dimethylamino-β-D-xylofuranoside de methyle 
• 143604-54-0 5-O-Benzyl-2,3-didesoxy-3-dimethylamino-2-fluoro-β-D-xylofuranoside de methyle 
• 143604-43-7 5-O-Benzyl-3-desoxy-3-dimethylamino-2-O-methanesulfonyl-β-D-xylofuranoside de methyle 
• 143604-45-9 5-O-Benzyl-2-desoxy-2-dimethylamino-3-O-methanesulfonyl-β-D-arabinofuranoside de methyle 

Relevant articles and documents

Preparation of methyl 2,3-anhydro- and 2,3-o-sulfinylfuranosides from unprotected furanosides using the Mitsunobu reaction

A new two step procedure for the synthesis of methyl 2,3-anhydro-α-D-lyxofuranoside and methyl 2,3-anhydro-β-D-ribofuranoside from D-xylose involving the intramolecular Mitsunobu reaction is presented. Likewise, methyl 2,3-anhydro-α-L-lyxofuranoside is obtained from L-arabinose. Cyclic sulfites with D-ribo configuration, synthetic equivalents of the corresponding anhydrosugars, are prepared in three steps from D-ribose.