490028-21-2

Basic information

• Product Name: 3-(Acetyloxy)-5-iodophenol-2’,3’,4’-tri-O-acetyl-β-D-glucuronide Methyl Ester
• Synonyms: 3-(Acetyloxy)-5-iodophenol-2’,3’,4’-tri-O-acetyl-β-D-glucuronide Methyl Ester;3-(Acetyloxy)-5-iodophenyl-β-D-glucopyranosiduronic Acid Methyl Ester Triacetate
• CAS NO: 490028-21-2
• Molecular Formula: C21H23IO12
• Molecular Weight: 594.30459
• Product Categories: Aromatics;Glucuronides;Heterocycles;Intermediates
• Mol File: 490028-21-2.mol
• Article Data: 0

Chemical Properties

• Boiling Point: 592.302°C at 760 mmHg
• Flash Point: 312.013°C
• Appearance: /
• Density: 1.627g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.569
• Storage Temp.: -20°C Freezer
• Solubility: Chloroform (Slightly), Methanol (Slightly)
• CAS DataBase Reference: 3-(Acetyloxy)-5-iodophenol-2’,3’,4’-tri-O-acetyl-β-D-glucuronide Methyl Ester(CAS DataBase Reference)
• NIST Chemistry Reference: 3-(Acetyloxy)-5-iodophenol-2’,3’,4’-tri-O-acetyl-β-D-glucuronide Methyl Ester(490028-21-2)
• EPA Substance Registry System: 3-(Acetyloxy)-5-iodophenol-2’,3’,4’-tri-O-acetyl-β-D-glucuronide Methyl Ester(490028-21-2)

Safety Data

• Hazardous Substances Data: 490028-21-2(Hazardous Substances Data)

Usage

Description

3-(Acetyloxy)-5-iodophenol-2’,3’,4’-tri-O-acetyl-β-D-glucuronide Methyl Ester is a white solid that serves as an intermediate in the synthesis of glucuronide conjugates of trans-Resveratrol. 3-(Acetyloxy)-5-iodophenol-2’,3’,4’-tri-O-acetyl-β-D-glucuronide Methyl Ester is characterized by its unique chemical structure, which includes an acetyloxy group, an iodine atom, and a β-D-glucuronide methyl ester moiety.

Uses

Used in Pharmaceutical Industry:
3-(Acetyloxy)-5-iodophenol-2’,3’,4’-tri-O-acetyl-β-D-glucuronide Methyl Ester is used as an intermediate for the synthesis of glucuronide conjugates of trans-Resveratrol. Trans-Resveratrol is a naturally occurring polyphenol with various pharmacological properties, including antioxidant, anti-inflammatory, and anti-cancer activities. The glucuronide conjugates of trans-Resveratrol are formed to improve its solubility, bioavailability, and stability, which are essential for its pharmaceutical applications.
Used in Research and Development:
3-(Acetyloxy)-5-iodophenol-2’,3’,4’-tri-O-acetyl-β-D-glucuronide Methyl Ester is also used in research and development for the study of glucuronidation, a crucial metabolic pathway in the body. 3-(Acetyloxy)-5-iodophenol-2’,3’,4’-tri-O-acetyl-β-D-glucuronide Methyl Ester can be utilized to investigate the role of glucuronidation in drug metabolism, detoxification, and the development of new drugs with improved pharmacokinetic properties.
Used in Chemical Synthesis:
As a white solid with unique chemical properties, 3-(Acetyloxy)-5-iodophenol-2’,3’,4’-tri-O-acetyl-β-D-glucuronide Methyl Ester can be employed in various chemical synthesis processes. Its versatile structure allows for further functionalization and modification, making it a valuable building block for the development of new compounds with potential applications in various industries, such as pharmaceuticals, agrochemicals, and materials science.

InChI:InChI=1/C21H23IO12/c1-9(23)29-14-6-13(22)7-15(8-14)33-21-19(32-12(4)26)17(31-11(3)25)16(30-10(2)24)18(34-21)20(27)28-5/h6-8,16-19,21H,1-5H3/t16-,17-,18?,19-,21+/m1/s1