4906-28-9

Basic information

• Product Name: 4-Butoxy-3-nitrobenzoic acid
• Synonyms: 4-Butoxy-3-nitrobenzoic acid
• CAS NO: 4906-28-9
• Molecular Formula: C₁₁H₁₃NO₅
• Molecular Weight: 239.22
• Mol File: 4906-28-9.mol
• Article Data: 4

Chemical Properties

• Melting Point: 166-167 °C
• Boiling Point: 397.115°C at 760 mmHg
• Flash Point: 193.969°C
• Appearance: /
• Density: 1.277g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.557
• PKA: 3.85±0.10(Predicted)
• CAS DataBase Reference: 4-Butoxy-3-nitrobenzoic acid(CAS DataBase Reference)
• NIST Chemistry Reference: 4-Butoxy-3-nitrobenzoic acid(4906-28-9)
• EPA Substance Registry System: 4-Butoxy-3-nitrobenzoic acid(4906-28-9)

Safety Data

• Hazardous Substances Data: 4906-28-9(Hazardous Substances Data)

Usage

General Description

4-Butoxy-3-nitrobenzoic acid is a chemical compound with the molecular formula C11H13NO5. It is a derivative of benzoic acid, containing a nitro group and a butoxy group attached to the benzene ring. 4-Butoxy-3-nitrobenzoic acid is commonly used in the synthesis of various pharmaceuticals and agrochemicals due to its diverse range of applications. It is also known for its potential use as an anti-inflammatory and analgesic agent. 4-Butoxy-3-nitrobenzoic acid is a yellow crystalline powder with a melting point of 168-170°C and it is slightly soluble in water. It is important to handle this compound with care, as it may cause skin and eye irritation.

InChI:InChI=1/C11H13NO5/c1-2-3-6-17-10-5-4-8(11(13)14)7-9(10)12(15)16/h4-5,7H,2-3,6H2,1H3,(H,13,14)

Upstream product

• 616-82-0 3-nitro-4-hydroxybenzoic acid 
• 19013-10-6 ethyl 4-hydroxy-3-nitrobenzoate 
• 778-28-9 butyl para-toluenesulfonate 

Relevant articles and documents

N-(3-nitro-4-alkoxybenzoyl)amino acid compounds as well as preparation method and application thereof

The invention discloses N-(3-nitro-4-alkoxybenzoyl)amino acid compounds as well as a preparation method and an application thereof and belongs to the field of medicines. 4-hydroxy-3-nitrobenzoic acidis subjected to methanol esterification, bromo-alkane substitution, hydrolysis and chlorination and then acylated with L-phenylglycine, R2 which is L-phenylglycine sodium salt is obtained, and the N-(3-nitro-4-alkoxybenzoyl)amino acid compounds are obtained after hydrolysis. The N-(3-nitro-4-alkoxybenzoyl)amino acid compounds have novel chemical structures, have good effects in an in-vitro xanthine oxidase inhibition activity test and can be used for treating and preventing gout diseases.

Substituted N-aryl heterocycles, process for their preparation and their use as medicaments

The invention relates to substituted N-aryl heterocycles and to the physiologically tolerated salts and physiologically functional derivatives thereof. Compounds of the formula I in which the radicals have the stated meanings, the N-oxides and the physiologically tolerated salts thereof and process for the preparation thereof are described. The compounds are suitable for example as anorectic agents.