4914-12-9

Basic information

• Product Name: Phosphonic acid, [(2-nitrophenyl)methyl]-, diethyl ester
• CAS NO: 4914-12-9
• Molecular Formula: C11H16NO5P
• Molecular Weight: 273.226
• Mol File: 4914-12-9.mol
• Article Data: 21

Chemical Properties

• CAS DataBase Reference: Phosphonic acid, [(2-nitrophenyl)methyl]-, diethyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: Phosphonic acid, [(2-nitrophenyl)methyl]-, diethyl ester(4914-12-9)
• EPA Substance Registry System: Phosphonic acid, [(2-nitrophenyl)methyl]-, diethyl ester(4914-12-9)

Safety Data

• Hazardous Substances Data: 4914-12-9(Hazardous Substances Data)

Upstream product

• 769907-13-3 2-nitrobenzylhydrazine 
• 122-52-1 triethyl phosphite 
• 3958-60-9 2-nitrophenylmethyl bromide 
• 762-04-9 phosphonic acid diethyl ester 
• 78-40-0 triethyl phosphate 
• 88-72-2 1-methyl-2-nitrobenzene 

Downstream Products

• 177284-52-5 diethyl α,α-difluoro-2-nitrobenzylphosphonate 
• 503856-36-8 diethyl [difluoro(2-aminophenyl)methyl]phosphonate 
• 303040-12-2 diethyl 2-(octanoylamino)benzylphosphonate 
• 303040-57-5 diethyl difluoro[2-(octanoylamino)phenyl]methylphosphonate 

Relevant articles and documents

Visible-light-mediated phosphonylation reaction: formation of phosphonates from alkyl/arylhydrazines and trialkylphosphites using zinc phthalocyanine

In this work, we developed a ligand- and base-free visible-light-mediated protocol for the photoredox syntheses of arylphosphonates and, for the first time, alkyl phosphonates. Zinc phthalocyanine-photocatalyzed Csp2-P and Csp3-P bond formations were efficiently achieved by reacting aryl/alkylhydrazines with trialkylphosphites in the presence of air serving as an abundant oxidant. The reaction conditions tolerated a wide variety of functional groups.

Tunable photophysical properties of thiophene based chromophores: A conjoined experimental and theoretical investigation

In this paper we report the synthesis and photophysical properties of six novel thiophene derivatives (ThD) with D-π-A structure. The subject of this work is three nitrophenyls (1) BT-Th-NO2 and three benzonitriles (2) BT-Th-CN, substituted at

Discovery and characterization of aryl isonitriles as a new class of compounds versus methicillin- and vancomycin-resistant Staphylococcus aureus

Methicillin- and vancomycin-resistant Staphylococcus aureus (MRSA and VRSA) have emerged as a global health concern. A new class of compounds featuring an aryl isonitrile moiety has been discovered that exhibits potent inhibitory activity against several clinically-relevant MRSA and VRSA isolates. Structure-activity relationship studies have been conducted to identify the aryl isonitrile group as the key functional group responsible for the observed antibacterial activity. The most potent antibacterial aryl isonitrile analogs (MIC 2 μM) did not show any toxicity against mammalian cells up to a concentration of 64 μM.