491610-80-1Relevant articles and documents
Antioxidant and radical scavenging activity of synthetic analogs of desferrithiocin
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, (2008/06/13)
Free radicals and reactive oxygen species have the potential to damage a wide variety of organic molecules, typically by oxidizing certain moieties. The present invention includes methods of using aryl-substituted heterocyclic compounds as antioxidants, a
Desferrithiocin analogue based hexacoordinate iron(III) chelators
Bergeron, Raymond J.,Huang, Guangfei,Weimar, William R.,Smith, Richard E.,Wiegand, Jan,McManis, James S.
, p. 16 - 24 (2007/10/03)
Traditional thinking has been that hexacoordinate Fe(III) ligands are more effective at preventing iron's interactions with reactive oxygen species, most particularly the Fe(II)-mediated reduction of hydrogen peroxide to the hydroxyl radical (i.e., Fenton