491842-73-0Relevant articles and documents
Stable oligonucleotide-directed triplex formation at target sites with CG interruptions: Strong sequence-specific recognition by 2′,4′-bridged nucleic-acid-containing 2-pyridones under physiological conditions
Obika, Satoshi,Hari, Yoshiyuki,Sekiguchi, Mitsuaki,Imanishi, Takeshi
, p. 4796 - 4802 (2002)
A sequence of double-stranded DNA (dsDNA) which can be recognized by a triplex-forming oligonucleotide (TFO) is limited to a homopurine-homopyrimidine sequence. To develop novel nucleoside analogues which recognize CG interruption in homopurine-homopyrimi