4919-10-2 Usage
General Description
7-Methyl-1,2,4-triazolo[4,3-a]pyridine, also known as MTR, is a chemical compound with a molecular formula C6H6N4. It is a heterocyclic compound that consists of a pyridine ring fused with a triazolopyridine ring. MTR is commonly used as a building block in the synthesis of pharmaceuticals and agrochemicals, as well as in the preparation of various substituted derivatives. It exhibits potential antifungal and herbicidal activities, making it a valuable component in the development of new drugs and agricultural products. MTR is also utilized in the manufacturing of dyes, pigments, and other organic compounds. As a versatile and important chemical compound, MTR has various applications in the fields of medicine, agriculture, and chemical industries.
Check Digit Verification of cas no
The CAS Registry Mumber 4919-10-2 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 4,9,1 and 9 respectively; the second part has 2 digits, 1 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 4919-10:
(6*4)+(5*9)+(4*1)+(3*9)+(2*1)+(1*0)=102
102 % 10 = 2
So 4919-10-2 is a valid CAS Registry Number.
InChI:InChI=1/C7H7N3/c1-6-2-3-10-5-8-9-7(10)4-6/h2-5H,1H3
4919-10-2Relevant articles and documents
Metal free [4+1] and [5+1] annulation reactions to prepare heterocycles using DMF and its derivatives as one-carbon source
Liu, Lingfeng,Qiao, Chunhua,Shen, Bei,Xu, Yiwen
, (2020/04/01)
1,2,4-Triazolo[3,4-a]pyridines and related heterocycles and substituted triazines were commonly discovered scaffolds in a variety of pharmaceutical and agrochemical agents. Herein, we report a highly efficient and practical method using DMF and its derivative for the [4+1] and [5+1] annulation reactions to prepare these heterocycles. This metal free reaction takes advantages of shelf stable DMF as solvent and carbon donor, imidazole chloride as a catalyst, the mild reaction condition tolerates a broad substrate range and substitutes. The prepared 3-unsubstituted 1,2,4-triazolo[3,4-a]pyridine and derivatives allow further introduction of a variety of functional group1 at 3-position.
