4919-16-8

Basic information

• Product Name: 3-propyl[1,2,4]triazolo[4,3-a]pyridine
• CAS NO: 4919-16-8
• Molecular Formula: C₉H₁₁N₃
• Molecular Weight: 161.2037
• Mol File: 4919-16-8.mol
• Article Data: 3

Chemical Properties

• Density: 1.15g/cm³
• Refractive Index: 1.615
• CAS DataBase Reference: 3-propyl[1,2,4]triazolo[4,3-a]pyridine(CAS DataBase Reference)
• NIST Chemistry Reference: 3-propyl[1,2,4]triazolo[4,3-a]pyridine(4919-16-8)
• EPA Substance Registry System: 3-propyl[1,2,4]triazolo[4,3-a]pyridine(4919-16-8)

Safety Data

• Hazardous Substances Data: 4919-16-8(Hazardous Substances Data)

Usage

General Description

3-propyl[1,2,4]triazolo[4,3-a]pyridine is a chemical compound with the molecular formula C8H10N4. It is a heterocyclic compound that consists of a pyridine ring fused to a triazolopyridine ring. 3-propyl[1,2,4]triazolo[4,3-a]pyridine is used in organic synthesis and medicinal chemistry as a building block for various pharmaceuticals. It has been studied for its potential role as an anti-cancer agent and as a modulator of the central nervous system. Additionally, it has been investigated for its potential use in the treatment of neurological disorders and as a potential drug target for various diseases.

Upstream product

• 4930-98-7 pyrid-2-ylhydrazine 
• 123-72-8 butyraldehyde 
• 10299-68-0 butyraldehyde pyridin-2-ylhydrazone 

Relevant articles and documents

Facile one pot synthesis of N-fused 1,2,4-triazoles via oxidative cyclisation using DDQ

A facile and expedient one pot synthesis of N-fused 1,2,4-triazoles from 2-hydrazinopyridines or 2-hydrazinopyrazines and aldehydes is described via oxidative cyclization using DDQ as a safe and convenient oxidizing agent and polyethylene glycol as recyclable reaction medium. This protocol is effective toward various substrates having different functionalities. The easy recyclability of the reaction medium makes the process economic and potentially viable for commercial applications.

A simple and efficient synthesis of 3,4,5-trisubstituted/N-fused 1,2,4-triazoles via ceric ammonium nitrate catalyzed oxidative cyclization of amidrazones with aldehydes using polyethylene glycol as a recyclable reaction medium

An environmentally benign protocol is described for the synthesis of 3,4,5-trisubstituted 1,2,4-triazoles and N-fused 1,2,4-triazoles via ceric ammonium nitrate catalyzed oxidative cyclization of amidrazones and aldehydes using polyethylene glycol as recyclable reaction medium. This protocol is effective toward various substrates having different functionalities. The easy recyclability of the reaction medium makes the process economic and potentially viable for commercial applications.