4934-25-2

Basic information

• Product Name: pyridin-4-ylmethyl 2-phenylacetate
• Synonyms: pyridin-4-ylmethyl 2-phenylacetate
• CAS NO: 4934-25-2
• Molecular Weight: 227.263
• Mol File: 4934-25-2.mol
• Article Data: 6

Chemical Properties

• CAS DataBase Reference: pyridin-4-ylmethyl 2-phenylacetate(CAS DataBase Reference)
• NIST Chemistry Reference: pyridin-4-ylmethyl 2-phenylacetate(4934-25-2)
• EPA Substance Registry System: pyridin-4-ylmethyl 2-phenylacetate(4934-25-2)

Safety Data

• Hazardous Substances Data: 4934-25-2(Hazardous Substances Data)

Upstream product

• 586-95-8 pyridine-4-methanol 
• 103-80-0 phenylacetyl chloride 
• 872-85-5 pyridine-4-carbaldehyde 

Downstream Products

• 103-82-2 phenylacetic acid 
• 2301-80-6 N-methyl-4-methylpyridinium iodide 

Relevant articles and documents

Carbon dots as photocatalysts for organic synthesis: Metal-free methylene-oxygen-bond photocleavage

We report for the first time that irradiation of four different citric acid-derived carbon dots (CDs), in the absence of any other redox mediators, promotes an organic reaction. In this proof-of-concept study methylene-oxygen bond reductive photocleavage in N-methyl-4-picolinium esters is demonstrated. Cyclic voltammetry and UV-Vis spectra of the CDs and of the esters indicate that photocleavage reactivity correlates with the redox properties and the relative energies expressed in the Fermi scale. A photo-fragmentation mechanism is proposed. This study offers a new possibility to employ inexpensive and readily available CDs to promote photo-organic reactions.

Visible Light Photorelease of Carboxylic Acids via Charge-Transfer Excitation of N-Methylpyridinium Iodide Esters

Iodide contrast sensitization to direct irradiation of charge transfer salts incurs carboxylic acid release via visible light absorption. The photochemical reduction of N-methyl-4-pyridinium iodide esters to release carboxylic acids is examined using 1H NMR analysis. Photolysis reactions are carried out under mild, biphasic solvent conditions using a household LED lamp. Carboxylic acid release is reported in high yields, and the viability of this method for synthetic chemistry is demonstrated through a macroscale reaction.

Photorelease of carboxylic acids, amino acids, and phosphates from N-alkylpicolinium esters using photosensitization by high wavelength laser dyes

Visible light (>450 nm) is used to efficiently cleave carboxylic acids, amino acids, and phosphates from their N-methyl picolinium esters. Photolysis using pyrromethene dyes PM 546 and PM 597 and also coumarin 6 as photosensitizers effects release of carboxylic acids, N-protected amino acids, and phosphates in quantitative yields. The effective rate of photorelease by the dyes, Φε, was found to be as high as 4500 M-1 cm-1. The photorelease proceeds through photoinduced electron transfer from the dye sensitizers to the N-methyl picolinium group. Fluorescence quenching and laser flash photolysis experiments support the photoinduced electron-transfer mechanism. Copyright