494209-46-0

Basic information

• Product Name: 4H-Indazol-4-one, 1-[3,5-bis(trifluoromethyl)phenyl]-1,5,6,7-tetrahydro-3-methyl-
• CAS NO: 494209-46-0
• Molecular Formula: C16H12F6N2O
• Molecular Weight: 362.274
• Mol File: 494209-46-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 4H-Indazol-4-one, 1-[3,5-bis(trifluoromethyl)phenyl]-1,5,6,7-tetrahydro-3-methyl-(CAS DataBase Reference)
• NIST Chemistry Reference: 4H-Indazol-4-one, 1-[3,5-bis(trifluoromethyl)phenyl]-1,5,6,7-tetrahydro-3-methyl-(494209-46-0)
• EPA Substance Registry System: 4H-Indazol-4-one, 1-[3,5-bis(trifluoromethyl)phenyl]-1,5,6,7-tetrahydro-3-methyl-(494209-46-0)

Safety Data

• Hazardous Substances Data: 494209-46-0(Hazardous Substances Data)

Upstream product

• 886-35-1 3,5-bis(trifluoromethyl)phenylhydrazine 
• 4056-73-9 2-acetyl-1,3-cyclohexanedione 

Downstream Products

• 627871-24-3 4-chloro-1-[3,5-di(trifluoromethyl)phenyl]-5-formyl-3-methyl-6,7-dihydroindazole 

Relevant articles and documents

1-(2-Quinoxalyl)-, 1-[3,5-di-(trifluoromethyl)phenyl]-, 1-(2-carboxyphenyl)-, and 1-ethoxycarbonyl-4-oxo-4,5,6,7-tetrahydroindazoles

The corresponding 1-(2-quinoxalyl)-, 1-[3,5-di(tridluoromethyl)phenyl]-, and 1-ethoxycarbonyl-3-methyl-4-oxo-4,5,6,7-tetrahydroindazoles have been obtained from reactions of 2-acetyl-1,3-cyclohexanedione, its 5,5-dimethyl and 5-(2-furyl) derivatives, with 2-hydrazinoquinoxaline, 3,5-di(trifluoromethyl)phenylhydrazine, and ethoxycarbonylhydrazine. On interaction with ethoxycarbonylhydrazine the intermediate 2-[1-(β-ethoxycarbonyl)hydrazino]ethylidene-1,3-cyclohexanediones were also isolated. From the potassium salt of 2-formyldimedone and 2-carboxyphenylhydrazine hydrochloride, 2-(2-carboxyphenyl)hydrazinomethylene-5,5-dimethyl-1,3-cyclohexanedione was obtained, the cyclization of which in ethanol in the presence of HCl led to 1-(2-carboxyphenyl)- and 1-(2-ethoxycarbonylphenyl)-6,6-dimethyl-4-oxo-4,5,6,7 -tetrahydroindazole.