495-31-8

Basic information

• Product Name: Nodakenin
• Synonyms: NODAKENIN;(2R)-2-[2-[(2S,3R,4S,5S,6R)-3,4,5-Trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxypropan-2-yl]-2,3-dihydrofuro[3,2-g]chromen-7-one;(R)-2-[1-(β-D-Glucopyranosyloxy)-1-methylethyl]-2,3-dihydro-7H-furo[3,2-g][1]benzopyran-7-one;2-(7-Oxo-2,3-dihydro-7H-furo[3,2-g]chromen-3-yl)-2-propanyl β-D-glucopyranoside;Nodakenin, 98%, from Angelica decursiva (Miq.) Franch. & Sav.
• CAS NO: 495-31-8
• Molecular Formula: C₂₀H₂₄O₉
• Molecular Weight: 408.4
• Product Categories: chemical reagent;pharmaceutical intermediate;phytochemical;reference standards from Chinese medicinal herbs (TCM).;standardized herbal extract
• Mol File: 495-31-8.mol
• Article Data: 1

Chemical Properties

• Melting Point: melting at 216°
• Boiling Point: 635.4 °C at 760 mmHg
• Flash Point: 225.4 °C
• Appearance: /
• Density: 1.51 g/cm³
• Vapor Pressure: 5.12E-17mmHg at 25°C
• Refractive Index: 1.65
• Storage Temp.: 2-8°C(protect from light)
• Solubility: Chloroform (Slightly, Sonicated), DMSO (Slightly)
• PKA: 12.90±0.70(Predicted)
• CAS DataBase Reference: Nodakenin(CAS DataBase Reference)
• NIST Chemistry Reference: Nodakenin(495-31-8)
• EPA Substance Registry System: Nodakenin(495-31-8)

Safety Data

• Safety Statements: 24/25
• Hazardous Substances Data: 495-31-8(Hazardous Substances Data)

Usage

Description

Nodakenin is a bioactive compound derived from the roots of the Nodakenin plant, known for its various pharmacological properties. It possesses antiviral, anti-inflammatory, and vasodilatory effects, making it a potential candidate for various therapeutic applications.

Uses

Used in Pharmaceutical Industry:
Nodakenin is used as an antiviral agent for inhibiting the influenza virus, including Nodakenin and/or Nodakenetin. It demonstrates effectiveness in preventing the replication and spread of the virus, offering potential benefits in the treatment and prevention of influenza-related illnesses.
Used in Antiviral Applications:
Nodakenin is employed as an antiviral agent, particularly against the influenza virus. It interferes with the virus's ability to replicate and spread, providing a potential therapeutic option for the treatment and prevention of influenza infections.
Used in Inflammatory Conditions:
Due to its anti-inflammatory properties, Nodakenin may also be used in the treatment of various inflammatory conditions. It can help alleviate symptoms and reduce the severity of inflammation, offering potential benefits for patients suffering from such conditions.
Used in Cardiovascular Health:
Nodakenin's vasodilatory effects make it a potential candidate for improving cardiovascular health. It may be used to treat conditions related to blood vessel constriction and hypertension, promoting better blood flow and overall cardiovascular function.

InChI:InChI=1/C20H24O9/c1-20(2,29-19-18(25)17(24)16(23)14(7-21)28-19)11-8-26-13-6-12-9(5-10(11)13)3-4-15(22)27-12/h3-6,11,14,16-19,21,23-25H,7-8H2,1-2H3/t11?,14-,16-,17+,18-,19+/m1/s1

Upstream product

• 125497-23-6 Marmesinin-tetraacetat 
• 125497-23-6 Nodakenin-tetraacetat 
• 124-41-4 sodium methylate 
• 131623-14-8 6'-O-trans-feruloylnodakenin 

Downstream Products

• 495-32-9 marmesin 
• 495-32-9 marmesin 
• 495-32-9 (+)-marmesin 

Relevant articles and documents

Isolation of two new coumarin glycosides from Notopterygium forbesii and evaluation of a Chinese crude drug, Qiang-Huo, the underground parts of N. incisum and N. forbesii, by high-performance liquid chromatography

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