49629-37-0

Basic information

• Product Name: BUTTPARK 104\40-45
• Synonyms: BUTTPARK 104\40-45;2-(4-METHOXYBENZYLIDENE)-1-TETRALONE
• CAS NO: 49629-37-0
• Molecular Formula: C₁₈H₁₆O₂
• Molecular Weight: 264.32
• Mol File: 49629-37-0.mol
• Article Data: 38

Chemical Properties

• Appearance: /
• CAS DataBase Reference: BUTTPARK 104\40-45(CAS DataBase Reference)
• NIST Chemistry Reference: BUTTPARK 104\40-45(49629-37-0)
• EPA Substance Registry System: BUTTPARK 104\40-45(49629-37-0)

Safety Data

• Hazardous Substances Data: 49629-37-0(Hazardous Substances Data)

Upstream product

• 123-11-5 4-methoxy-benzaldehyde 
• 529-34-0 3,4-dihydronaphthalene-1(2H)-one 
• 105-13-5 4-Methoxybenzyl alcohol 
• 119-64-2 tetralin 
• 771-29-9 1,2,3,4-tetrahydro-1-naphthyl hydroperoxide 
• 14397-61-6 3,4-dihydronaphthalen-1(2H)-one-2,2-d₂ 

Downstream Products

• 66128-95-8 2-Cyano-3-(4-methoxy-phenyl)-N-methyl-3-(1-oxo-1,2,3,4-tetrahydro-naphthalen-2-yl)-propionamide 
• 83388-31-2 4-(4-Methoxy-phenyl)-3-phenyl-5,6-dihydro-benzo[h]quinoline 
• 134408-33-6 3-methyl-4-phenyl-3,4,5,6-tetrahydrobenzoquinazoline-2(1H)-thione 
• 134408-32-5 9-(4-chlorophenyl)-7-(4-methoxyphenyl)-6,7-dihydro-5H-benzo[h]thiazolo[2,3-b]quinazoline 
• 78364-69-9 2-Bromo-2-[bromo-(4-methoxy-phenyl)-methyl]-3,4-dihydro-2H-naphthalen-1-one 
• 84354-02-9 2-(dimethoxymethyl)-2-(4-methoxyphenyl)-1,2,3,4-tetrahydronaphthalene-1-one 
• 83388-40-3 14-(4-Methoxy-phenyl)-12,13-dihydro-6H-6,7-diaza-dibenzo[a,h]anthracen-5-one 
• 83388-36-7 2-[2-Hydroxy-4-(4-methoxy-phenyl)-5,6-dihydro-benzo[h]quinolin-3-yl]-benzamide 
• 97145-61-4 4-(4-methoxyphenyl)-5,6-dihydrobenzo[h]quinazolin-2-amine 
• 49545-52-0 3,3a-trans-2-acetyl-3-p-anisyl-2H-3,3a,4,5-tetrahydronaphtho<1,2-c>pyrazole 
• 49545-52-0 3,3a-cis-2-acetyl-3-p-anisyl-2H-3,3a,4,5-tetrahydronaphtho<1,2-c>pyrazole 
• 109329-44-4 4-(4-Methoxy-phenyl)-3-phenyl-3,4,5,6-tetrahydro-1H-benzo[h]quinolin-2-one 
• 94990-81-5 4-(4-Methoxy-phenyl)-1,4,5,6-tetrahydro-naphtho[1,2-d][1,3]thiazin-2-ylideneamine; hydrochloride 
• 106319-26-0 2-phenyl-4-(4-methoxyphenyl)-3,4,5,6-tetrahydrobenzoquinazoline 

Relevant articles and documents

A class of 2-benzylene tetrahydronaphthalone derivatives and preparation methods and applications thereof

The present invention relates to the field of biotechnology, discloses a class of 2-benzylene tetrahydrophthalone derivatives and preparation methods and applications thereof. 2-Benzylene tetrahydronaphthalone derivative having the following structural formula, wherein R1 is selected from chlorine, bromine, iodine, alkyl, alkoxy, substituted or unsubstituted amino, alkylthio, alkyneoxy, hydroxy or hydroxymethyl group; R2, R3, R4 are hydrogen or carboxyl-containing substituents, and R2, R3, or R4 At least one of them is a carboxyl-containing substituent group. The present invention innovatively proposes a class of 2-benzylene tetrahydronaphthalone derivatives as a new skeleton of firefly luciferase inhibitors. A class of 2-benzylene tetrahydronaphthone derivatives of the present invention having a highly efficient inhibitor of nanomolar and a nanamol IC50; by competing with D- fluorescein reversibly inhibits firefly luciferase, and exhibits a high effect of firefly glowworm luciferase inhibition at the enzyme, intracellular and in vivo levels; at the same time, it is shown that it has good biocompatibility and application potential.

From Celecoxib to a Novel Class of Phosphodiesterase 5 Inhibitors: Trisubstituted Pyrazolines as Novel Phosphodiesterase 5 Inhibitors with Extremely High Potency and Phosphodiesterase Isozyme Selectivity

A ligand-based approach involving systematic modifications of a trisubstituted pyrazoline scaffold derived from the COX2 inhibitor, celecoxib, was used to develop novel PDE5 inhibitors. Novel pyrazolines were identified with potent PDE5 inhibitory activit

A simple iron-catalyst for alkenylation of ketones using primary alcohols

Herein, we developed a simple iron-catalyzed system for the α-alkenylation of ketones using primary alcohols. Such acceptor-less dehydrogenative coupling (ADC) of alcohols resulted in the synthesis of a series of important α,β-unsaturated functionalized ketones, having aryl, heteroaryl, alkyl, nitro, nitrile and trifluoro-methyl, as well as halogen moieties, with excellent yields and selectivity. Initial mechanistic studies, including deuterium labeling experiments, determination of rate and order of the reaction, and quantitative determination of H2 gas, were performed. The overall transformations produce water and dihydrogen as byproducts.