49639-13-6

Basic information

• Product Name: Benzoyl chloride, 2-(methylsulfonyl)-
• CAS NO: 49639-13-6
• Molecular Formula: C8H7ClO3S
• Molecular Weight: 218.661
• Mol File: 49639-13-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Benzoyl chloride, 2-(methylsulfonyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzoyl chloride, 2-(methylsulfonyl)-(49639-13-6)
• EPA Substance Registry System: Benzoyl chloride, 2-(methylsulfonyl)-(49639-13-6)

Safety Data

• Hazardous Substances Data: 49639-13-6(Hazardous Substances Data)

Upstream product

• 19093-34-6 2-(methylsulfinyl)benzoic acid 
• 33963-55-2 2-(methylsulfonyl)benzoic acid 

Downstream Products

• 75473-10-8 2-Mesylbenzoyl-malonsaeurediethylester 
• 33963-55-2 2-(methylsulfonyl)benzoic acid 
• 867290-77-5 2-chloro-N'-(2-(methylsulfonyl)benzoyl)benzohydrazide 
• 92474-86-7 o-Methylsulfon-phenylaethylenglykol 
• 111211-66-6 ω-Acetoxy-o-methylsulfon-acetophenon 
• 91061-66-4 o-Methylsulfon-propiophenon 
• 5395-89-1 2-methylsulphonylbenzaldehyde 
• 99793-47-2 1-(4-Fluoro-phenyl)-5-(2-methanesulfonyl-phenyl)-3-methylsulfanyl-1H-[1,2,4]triazole 
• 75473-45-9 5-(2-Methanesulfonyl-phenyl)-7-nitro-1,3-dihydro-thieno[2,3-e][1,4]diazepin-2-one 
• 75473-44-8 7-Chloro-5-(2-methanesulfonyl-phenyl)-1,3-dihydro-thieno[2,3-e][1,4]diazepin-2-one 
• 75473-18-6 2-Chloro-N-[3-(2-methanesulfonyl-benzoyl)-thiophen-2-yl]-acetamide 
• 75473-36-8 2-Amino-N-[3-(2-methanesulfonyl-benzoyl)-thiophen-2-yl]-acetamide 
• 75473-23-3 2-Iodo-N-[3-(2-methanesulfonyl-benzoyl)-thiophen-2-yl]-acetamide 
• 75473-33-5 5-(2-Methanesulfonyl-phenyl)-1,3-dihydro-thieno[2,3-e][1,4]diazepin-2-one 

Relevant articles and documents

Improved synthesis of sterically encumbered heteroaromatic biaryls from aromatic β-keto esters

A protocol for the synthesis of hindered 4-aryl 2-aminopyrimidines from β–keto esters is described. The process employs trifluoroethanol as an essential additive to promote the guanidine condensation reaction, enabling the synthesis of 25 aryl- and heteroaryl substituted aminopyrimidines in good yields and high purities with no column chromatography. The conditions described herein are readily scalable and have been employed in the large-scale synthesis of the clinical A2a/A2bR antagonist AB928.