49673-74-7

Basic information

• Product Name: 3-Phenylcyclohexanol
• Synonyms: 3-Phenylcyclohexanol
• CAS NO: 49673-74-7
• Molecular Formula: C₁₂H₁₆O
• Molecular Weight: 176.2548
• Mol File: 49673-74-7.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 295.8°Cat760mmHg
• Flash Point: 113.3°C
• Appearance: /
• Density: 1.051g/cm³
• Vapor Pressure: 0.000673mmHg at 25°C
• Refractive Index: 1.553
• CAS DataBase Reference: 3-Phenylcyclohexanol(CAS DataBase Reference)
• NIST Chemistry Reference: 3-Phenylcyclohexanol(49673-74-7)
• EPA Substance Registry System: 3-Phenylcyclohexanol(49673-74-7)

Safety Data

• Hazardous Substances Data: 49673-74-7(Hazardous Substances Data)

Usage

General Description

3-Phenylcyclohexanol is a chemical compound with the molecular formula C12H16O. It is a colorless to pale yellow viscous liquid that is used as a fragrance ingredient or a flavoring agent in various products. 3-Phenylcyclohexanol is derived from the reaction of cyclohexanone with phenylmagnesium bromide. It is commonly used in the production of perfumes, soaps, and other personal care products due to its pleasant floral aroma. Additionally, it can also be utilized in the synthesis of other organic compounds, such as pharmaceuticals and other fragrance chemicals. However, this compound should be handled with care as it may cause skin and eye irritation and should be stored in a cool, dry place away from direct sunlight.

InChI:InChI=1/C12H16O/c13-12-8-4-7-11(9-12)10-5-2-1-3-6-10/h1-3,5-6,11-13H,4,7-9H2

Upstream product

• 493-72-1 5-phenyl-cyclohexane-1,3-dione 
• 51367-64-7 3-chloro-5-phenylcyclohex-2-en-1-one 
• 141832-01-1 4,4-Bis-benzenesulfonyl-3-phenyl-cyclohexanone 
• 144150-82-3 3-oxo-5-phenylcyclohex-1-en-1-yl 4-methylbenzene-1-sulfonate 
• 20795-53-3 3-phenylcyclohexanone 
• 827-52-1 1-phenyl-1-cyclohexane 
• 64-17-5 ethanol 
• 39082-44-5 1,1-bis(phenylsulfonyl)-2-phenylethene 
• 100-52-7 benzaldehyde 
• 10345-87-6 3-phenylcyclohex-2-enone 
• 108-05-4 vinyl acetate 
• 580-51-8 [1,1'-biphenyl]-3-ol 
• 98-80-6 phenylboronic acid 
• 930-68-7 cyclohexenone 

Downstream Products

• 20795-53-3 3-phenylcyclohexanone 
• 38383-07-2 1-bromo-3-phenyl-cyclohexane 
• 22147-17-7 cis-3-Phenyl-cyclohexanol 
• 21152-27-2 cis-3-Phenylcyclohexylacetat 
• 22147-17-7 cis-3-phenylcyclohexanol 
• 827-52-1 1-phenyl-1-cyclohexane 
• 5458-48-0 4-cyclohexylnitrobenzene 
• 108062-26-6 (3-phenyl-cyclohexyl)-acetic acid 
• 859819-78-6 (3-phenyl-cyclohexyl)-malonic acid 
• 59192-35-7 4-Oxo-4-[4-(3-oxo-cyclohexyl)-phenyl]-butyric acid 
• 19992-43-9 (1RS,3SR)-3-phenylcyclohexanamine 
• 1384865-47-7 (1SR,3SR)-3-phenylcyclohexyl methanesulfonate 
• 19992-43-9 (1RS,3SR)-3-phenylcyclohexanamine 

Relevant articles and documents

Ir(NHC)-Catalyzed Synthesis of β-Alkylated Alcohols via Borrowing Hydrogen Strategy: Influence of Bimetallic Structure

Multi N-heterocyclic carbene(NHC)-modified iridium catalysts were employed in the β-alkylation of alcohols; dimerization of primary alcohols (Guerbet reaction), cross-coupling of secondary and primary alcohols, and intramolecular cyclization of alcohols. Mechanistic studies of Guerbet reaction, including kinetic experiments, mass analysis, and density functional theory (DFT) calculation, were employed to explain the fast reaction promoted by bimetallic catalysts, and the dramatic reactivity increase of monometallic catalysts at the late stage of the reaction. (Figure presented.).

Stereoselective synthesis of carbocyclic analogues of the nucleoside Q precursor (PreQ0)

A convergent and stereoselective synthesis of chiral cyclopentyl- and cyclohexylamine derivatives of nucleoside Q precursor (PreQ0) has been accomplished. This synthetic route allows for an efficient preparation of 4-substituted analogues with

Selective electrochemical reduction of cinnamyl ethers in the presence of other allylic C-O bonds

Several conduritol derivatives protected as allyl and cinnamyl ethers were subjected to electrochemical reduction at a mercury cathode, resulting in selective removal of the cinnamyl group.