497144-17-9Relevant articles and documents
Concise Synthesis of the Tricyclic Core of Salimabromide
Schmalzbauer, Bj?rn,Menche, Dirk
, p. 2956 - 2959 (2015)
A concise synthesis of the tricyclic core 2 of the structurally unique marine myxobacterial natural product salimabromide has been developed. Compound 2 contains the tetraline subunit including the two quaternary centers and the eight-membered ring of sal
Synthesis of racemic Δ3-2-hydroxybakuchiol and its analogues
Shi, Lei,Lei, Xinsheng,Zhang, Jiange,Lin, Guoqiang
experimental part, p. 555 - 564 (2010/06/14)
The first synthetic approach to (±)-Δ3-2- hydroxybakuchiol (=4-[(1E,5E)-3-ethenyl-7-hydroxy-3,7-dimethylocta-1,5-dien-1- yl]phenol; 14) and its analogues 13a - 13f was developed by 12 steps (Schemes 2 and 3). The key features of the approach are the construction of the quaternary C-center bearing the ethenyl group by a Johnson - Claisen rearrangement (→6); and of an (E)-alkenyl iodide via a Takai - Utimoto reaction (→11); and an arylation via a Negishi cross-coupling reaction (→12e - 12f).
Asymmetric total synthesis of martinelline and martinellic acid
Ikeda, Shuhei,Shibuya, Masatoshi,Iwabuchi, Yoshiharu
, p. 504 - 506 (2007/10/03)
Herein, we describe the first asymmetric total synthesis of (-)-martinelline ((-)-2) and the second total synthesis of (-)-martinellic acid ((-)-1) by employing a tandem Mukaiyama-Mannich reaction/aminal cyclization as the key step. The Royal Society of C