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497834-29-4

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497834-29-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 497834-29-4 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 4,9,7,8,3 and 4 respectively; the second part has 2 digits, 2 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 497834-29:
(8*4)+(7*9)+(6*7)+(5*8)+(4*3)+(3*4)+(2*2)+(1*9)=214
214 % 10 = 4
So 497834-29-4 is a valid CAS Registry Number.

497834-29-4Downstream Products

497834-29-4Relevant articles and documents

Long-chain aminoalcohol and diamine derivatives induce apoptosis through a caspase-3 dependent pathway

Del Olmo, Esther,Macho, Antonio,Alves, Mario,Lopez, Jose L.,Banoua, Fadwa,Muoz, Eduardo,San Feliciano, Arturo

, p. 2621 - 2626 (2002)

A number of long chain diamines and aminoalcohols and several of their alkyl, acyl and carbamoyl derivatives, have been synthesized and evaluated for their apoptotic activities using the Jurkat cell line. Apoptosis was measured by flow cytometry and the best results were found for the aminoalcohols displaying either a free alcohol or an amine with at least, one free hydrogen atom. The apoptotic pathway was mediated by a disruption of the mitochondria transmembrane potential and caspase-3 activation, inducing DNA fragmentation at the phase G1/S of the cell cycle.

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