49787-03-3

Basic information

• Product Name: Phenol, 4-(5-phenyl-1,2,4-oxadiazol-3-yl)-
• CAS NO: 49787-03-3
• Molecular Formula: C14H10N2O2
• Molecular Weight: 238.246
• Mol File: 49787-03-3.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: Phenol, 4-(5-phenyl-1,2,4-oxadiazol-3-yl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Phenol, 4-(5-phenyl-1,2,4-oxadiazol-3-yl)-(49787-03-3)
• EPA Substance Registry System: Phenol, 4-(5-phenyl-1,2,4-oxadiazol-3-yl)-(49787-03-3)

Safety Data

• Hazardous Substances Data: 49787-03-3(Hazardous Substances Data)

Upstream product

• 767-00-0 4-cyanophenol 
• 98-88-4 benzoyl chloride 
• 1219626-47-7 (Z)-N',4-dihydroxybenzimidamide 
• 49787-00-0 N',4-dihydroxybenzamidine 

Downstream Products

• 40678-81-7 2-methyl-2-[4-(5-phenyl-[1,2,4]oxadiazol-3-yl)-phenoxy]-propionic acid 

Relevant articles and documents

QUINOLINE AND QUINOXALINE DERIVATIVES AS INHIBITORS OF KINASE ENZYMATIC ACTIVITY

Compounds of formula (IA) or (IB), are inhibitors of aurora kinase activity: Formula (IA), (IB) wherein -L1Y1-[CH2]z- is a linker radical wherein Y1, L1 and z are as defined in the claims; R6 is C1-C4alkoxy, hydrogen or halo; W represents a bond, -CH2-, -O-, -S-, -S(=O)2-, or -NR5- where R5 is hydrogen or C1-C4 alkyl; Q is =N-, =CH- or =C(X1)- wherein X1 is cyano, cyclopropyl or halo; linker radicals L2 are as defined in the claims; R is a radical of formula (X) or (Y): wherein R1 is a carboxylic acid group (-COOH), or an ester group which is hydrolysable by one or more intracellular carboxylesterase enzymes to a carboxylic acid group; R4 is hydrogen; or optionally substituted C1-C6 alkyl, C3-C7 cycloalkyl, aryl, aryl(C1-C6 alkyl)-, heteroaryl, heteroaryl(C1-C6 alkyl)-, -(C=O)R3, -(C=O)OR3, or -(C=O)NR3 wherein R3 is hydrogen or optionally substituted (C1-C6)alkyl, C3-C7 cycloalkyl, aryl, aryl(C1-C6 alkyl)-, heteroaryl, or heteroaryl(C1-C6 alkyl)-; R41 is hydrogen or optionally substituted C1-C6 alkyl; and D is a monocyclic heterocyclic ring of 5 or 6 ring atoms.