4988-22-1

Basic information

• Product Name: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,8-dimethoxy-4H-chromen-4-one
• Synonyms: 3',4',5,7-Tetrahydroxy-3,8-dimethoxyflavone; 4H-1-benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,8-dimethoxy-; Flavone, 3',4',5,7-tetrahydroxy-3,8-dimethoxy-
• CAS NO: 4988-22-1
• Molecular Formula: C₁₇H₁₄O₈
• Molecular Weight: 346.2883
• Mol File: 4988-22-1.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 661.7°C at 760 mmHg
• Flash Point: 246.9°C
• Density: 1.65g/cm³
• Vapor Pressure: 4.09E-18mmHg at 25°C
• Refractive Index: 1.731
• CAS DataBase Reference: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,8-dimethoxy-4H-chromen-4-one(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,8-dimethoxy-4H-chromen-4-one(4988-22-1)
• EPA Substance Registry System: 2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-3,8-dimethoxy-4H-chromen-4-one(4988-22-1)

Safety Data

• Hazardous Substances Data: 4988-22-1(Hazardous Substances Data)

Usage

Type of compound

Flavone

Sources

Citrus fruits, Ginkgo biloba, and other medicinal herbs

Properties

+ Antioxidant
+ Anti-inflammatory
+ Anti-cancer
+ Neuroprotective
+ Anti-diabetic (improves insulin sensitivity and reduces blood glucose levels)
+ Hepatoprotective (protects the liver and may help in the treatment of liver diseases)
+ Potential in treating asthma and other respiratory conditions (due to its anti-inflammatory properties)

Therapeutic applications

Various potential health benefits and therapeutic applications are being studied.

Upstream product

• 7678-88-8 3',4',7-trihydroxy-3,5,8-trimethoxyflavone 
• 20972-77-4 Acetic acid 2-(3,4-diacetoxy-phenyl)-3,5,8-trimethoxy-4-oxo-4H-chromen-7-yl ester 
• 42923-40-0 2,4-dihydroxy-3,6,ω-trimethoxyacetophenone 
• 1592-48-9 3,4-bis-benzyloxy-benzoic acid-anhydride 
• 110193-73-2 3',4'-bis(benzyloxy)-7-hydroxy-3,5,8-trimethoxyflavone 

Downstream Products

• 489-35-0 gossypetin 

Relevant articles and documents

Polyoxygenated flavonoids from Eugenia edulis

Leaves of Eugenia edulis contain the new polyoxygenated flavonoid derivatives, gossypetin-3,8-dimethyl ether-5-O-β-glucoside; gossypetin-3,5-dimethyl ether, and myricetin-3,5,3′-trimethyl ether. In addition, ten known polyphenolics were also isolated and identified. All structures were established on the basis of chemical and spectral evidence, including ESI-MS and 13C NMR.