4988-33-4

Basic information

• Product Name: tetrahydro-2H-thiopyran 1,1-dioxide
• Synonyms: 2H-thiopyran, tetrahydro-, 1,1-dioxide; Tetrahydro-2H-thiopyran 1,1-dioxide; Thiacyclohexane 1,1-dioxide; Thiacyclohexane dioxide
• CAS NO: 4988-33-4
• Molecular Formula: C₅H₁₀O₂S
• Molecular Weight: 134.1967
• Mol File: 4988-33-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 183.7°C at 760 mmHg
• Flash Point: 44.4°C
• Density: 1.187g/cm³
• Vapor Pressure: 1.04mmHg at 25°C
• Refractive Index: 1.477
• CAS DataBase Reference: tetrahydro-2H-thiopyran 1,1-dioxide(CAS DataBase Reference)
• NIST Chemistry Reference: tetrahydro-2H-thiopyran 1,1-dioxide(4988-33-4)
• EPA Substance Registry System: tetrahydro-2H-thiopyran 1,1-dioxide(4988-33-4)

Safety Data

• Hazardous Substances Data: 4988-33-4(Hazardous Substances Data)

Upstream product

• 7647-01-0 hydrogenchloride 
• 17396-35-9 1,1-dioxotetrahydrothiopyran-4-one 
• 314056-83-2 (but-3-ene-1-sulfonylmethylselanyl)-benzene 
• 197148-70-2 hex-5-enoic acid 2-thioxo-2H-pyridin-1-yl ester 

Downstream Products

• 63149-24-6 4-(1,1,2-trimethyl-1H-benzo[e]indol-3-ium-3-yl)butane-1-sulfonate 
• 1220981-52-1 N-[1-(tetrahydro-1,1-dioxido-2H-thiopyran-2(S)-yl)cyclohexyl]-2-methyl-2-propane-(S)-sulfinamide 
• 1220981-53-2 N-[1-(tetrahydro-1,1-dioxido-2H-thiopyran-2(R)-yl)cyclohexyl]-2-methyl-2-propane-(S)-sulfinamide 
• 14856-64-5 2-phenyltetrahydro-2H-thiopyran 1,1-dioxide 

Relevant articles and documents

Radical [n + 1] annulations with sulfur dioxide

A new methodology for [n + 1] radical annulation using sulfur dioxide as a geminal radical acceptor/donor is presented. This methodology provides a novel route to the formation of five-, six-, and seven-membered cyclic sulfones utilizing a radical chain m

Ring closure of 2-thia- and 2-sulfonyl-5-hexenyl radicals

Reductive cyclisation of the 2-sulfonyl-5-hexenyl radical with tributyltin hydride in benzene at 80°C affords a 73:23 mixture of the sulfones derived from 5-exo- and 6-endo- ring closure with a small quantity (4%) of reduced material; under identical conditions, the 2-thia-5-hexenyl radical gives a 70:13:17 mixture of the corresponding sulfides. (C) 2000 Elsevier Science Ltd.