499140-11-3

Basic information

• Product Name: benzyl (2S,4S,5R)-4-methyl-5-phenyl-1,2,3-oxathiazolidine-2-oxide-3-carboxylate
• Synonyms: benzyl (2S,4S,5R)-4-methyl-5-phenyl-1,2,3-oxathiazolidine-2-oxide-3-carboxylate
• CAS NO: 499140-11-3
• Molecular Weight: 331.392
• Mol File: 499140-11-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: benzyl (2S,4S,5R)-4-methyl-5-phenyl-1,2,3-oxathiazolidine-2-oxide-3-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: benzyl (2S,4S,5R)-4-methyl-5-phenyl-1,2,3-oxathiazolidine-2-oxide-3-carboxylate(499140-11-3)
• EPA Substance Registry System: benzyl (2S,4S,5R)-4-methyl-5-phenyl-1,2,3-oxathiazolidine-2-oxide-3-carboxylate(499140-11-3)

Safety Data

• Hazardous Substances Data: 499140-11-3(Hazardous Substances Data)

Upstream product

• 104863-92-5 (1R,2S)-1-phenyl-2-benzyloxycarbonylamino-1-propanol 
• 501-53-1 benzyl chloroformate 
• 492-41-1 (1R,2S)-norephedrine 

Downstream Products

• 104863-92-5 (1R,2S)-1-phenyl-2-benzyloxycarbonylamino-1-propanol 
• 18689-86-6 (R)-methyl mesityl sulfoxide 
• 77333-17-6 (+)-(R)-mesityl p-tolyl sulphoxide 
• 1774-36-3 bis(4-methoxyphenyl) sulfoxide 
• 945-51-7 1,1'-sulfinylbisbenzene 
• 499140-17-9 (1R,2S)-2-{[(benzyloxy)carbonyl]amino}-1-phenylpropyl (S)-benzenesulfinate 
• 2211-89-4 diisopropyl sulfoxide 
• 67-68-5 dimethyl sulfoxide 
• 70-29-1 diethyl sulphide 

Relevant articles and documents

A General and Expeditious One-Pot Synthesis of Sulfoxides in High Optical Purity from Norephedrine-Derived Sulfamidites

A general and simple procedure for preparing any kind of enantiomerically enriched sulfoxide starting from norephedrine-derived N-benzyloxycarbonylsulfamidite 3a is reported. After one-pot reaction of 3a with RMgX, HBF4, and R'MgX, a variety of sulfoxides 6 are obtained in ee usually higher than 93% and isolated yields ranging between 50 and 78%. The obtained configuration is tunable by simply electing the order of the addition of the reagents.