499194-65-9

Basic information

• Product Name: Benzene, 1-methoxy-2-(1-phenyl-3-butenyl)-
• CAS NO: 499194-65-9
• Molecular Formula: C17H18O
• Molecular Weight: 238.329
• Mol File: 499194-65-9.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: Benzene, 1-methoxy-2-(1-phenyl-3-butenyl)-(CAS DataBase Reference)
• NIST Chemistry Reference: Benzene, 1-methoxy-2-(1-phenyl-3-butenyl)-(499194-65-9)
• EPA Substance Registry System: Benzene, 1-methoxy-2-(1-phenyl-3-butenyl)-(499194-65-9)

Safety Data

• Hazardous Substances Data: 499194-65-9(Hazardous Substances Data)

Upstream product

• 18146-00-4 allyloxytrimethylsilane 
• 100-52-7 benzaldehyde 
• 100-66-3 methoxybenzene 
• 24850-33-7 allyltributylstanane 
• 80735-94-0 1-Phenyl-3-buten-1-ol 
• 139284-72-3 4-trimethylsiloxy-4-phenyl-1-butene 
• 22788-49-4 2-methoxyphenyl(phenyl)methanol 
• 762-72-1 allyl-trimethyl-silane 

Downstream Products

• 1186642-20-5 C₁₇H₁₈O 

Relevant articles and documents

A convenient method for the synthesis of 4,4-diarylbut-1-enes via the successive allylation of aromatic aldehydes and the Friedel-Crafts alkylation reaction of aromatic nucleophiles with the intermediary benzyl silyl ethers using HfCl4 or Cl2Si(OTf)2

The three-component coupling reaction among aromatic aldehydes, allyltrimethylsilane and aromatic nucleophiles is efficiently performed by the promotion of HfCl4. A similar reaction occurs using allyltributyltin as the first nucleophile to aromatic aldehydes with a catalytic amount of Cl2Si(OTf)2 generated in situ from SiCl4 and AgOTf.

Secondary benzylation with benzyl alcohols catalyzed by a high-valent heterobimetallic Ir-Sn complex

(Chemical Equation Presented) A highly efficient secondary benzylation procedure has been demonstrated using a high-valent heterobimetallic complex [Ir2(COD)2(SnCls)2(Cl)2(μ-Cl) 2] 1 as the catalyst in 1,2-dichloroethane to afford the corresponding benzylated products in moderate to excellent yields. The reaction was performed not only with carbon nucleophiles (arenes and heteroarenes) but also with oxygen (alcohol), nitrogen (amide and sulfonamide), and sulfur (thiol) nucleophiles. Mechanistic investigation showed the intermediacy of the ether in this reaction. An electrophilic mechanism is proposed from Hammett correlation.