4999-02-4

Basic information

• Product Name: N-{4-[(2-oxopropyl)sulfonyl]phenyl}acetamide
• CAS NO: 4999-02-4
• Molecular Formula: C₁₁H₁₃NO₄S
• Molecular Weight: 255.2902
• Mol File: 4999-02-4.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 528.6°C at 760 mmHg
• Flash Point: 273.5°C
• Density: 1.313g/cm³
• Vapor Pressure: 2.91E-11mmHg at 25°C
• Refractive Index: 1.557
• CAS DataBase Reference: N-{4-[(2-oxopropyl)sulfonyl]phenyl}acetamide(CAS DataBase Reference)
• NIST Chemistry Reference: N-{4-[(2-oxopropyl)sulfonyl]phenyl}acetamide(4999-02-4)
• EPA Substance Registry System: N-{4-[(2-oxopropyl)sulfonyl]phenyl}acetamide(4999-02-4)

Safety Data

• Hazardous Substances Data: 4999-02-4(Hazardous Substances Data)

Upstream product

• 15898-43-8 sodium 4-acetamidobenzenesulfinate 
• 78-95-5 chloroacetone 
• 121-60-8 p-acetylaminobenzenesulfonyl chloride 

Downstream Products

• 792915-41-4 acetic acid-[4-(1-bromo-2-oxo-propane-1-sulfonyl)-anilide] 
• 861061-01-0 acetic acid-[N-bromo-4-(2-oxo-propane-1-sulfonyl)-anilide] 
• 792915-59-4 acetic acid-[4-(2-amino-4-methyl-thiazole-5-sulfonyl)-anilide] 
• 57946-90-4 2-bromo-4-methanesulfonylphenylamine 
• 861061-00-9 acetic acid-[2-bromo-4-(2-oxo-propane-1-sulfonyl)-anilide] 

Relevant articles and documents

Facile One-Pot Access to α-Diazo-β-ketosulfones from Sulfonyl Chlorides and α-Haloketones

A convenient one-pot approach to the preparation of α-diazo-β-ketosulfones from sulfonyl chlorides is described. It involves the conversion of the sulfonyl chloride to sodium sulfinate, alkylation of the latter with α-haloketones followed by diazo transfer using the 'sulfonyl-azide-free' ('SAFE') protocol in aqueous medium. The simple and expedient method relies on readily available starting materials and provides facile access to a wide variety of valuable diazo reagents for organic synthesis.