500-48-1Relevant articles and documents
Structure-guided design of novel thiazolidine inhibitors of O -Acetyl serine sulfhydrylase from mycobacterium tuberculosis
Poyraz, ?mer,Jeankumar, Variam Ullas,Saxena, Shalini,Schnell, Robert,Haraldsson, Martin,Yogeeswari, Perumal,Sriram, Dharmarajan,Schneider, Gunter
supporting information, p. 6457 - 6466 (2013/09/23)
The cysteine biosynthetic pathway is absent in humans but essential in microbial pathogens, suggesting that it provides potential targets for the development of novel antibacterial compounds. CysK1 is a pyridoxalphosphate- dependent O-acetyl sulfhydrylase