500003-02-1

Basic information

• Product Name: 1H-Indole-1-butanenitrile, 3-[2-(dimethylamino)ethyl]-4-(phenylmethoxy)-
• CAS NO: 500003-02-1
• Molecular Formula: C23H27N3O
• Molecular Weight: 361.487
• Mol File: 500003-02-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Indole-1-butanenitrile, 3-[2-(dimethylamino)ethyl]-4-(phenylmethoxy)-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-1-butanenitrile, 3-[2-(dimethylamino)ethyl]-4-(phenylmethoxy)-(500003-02-1)
• EPA Substance Registry System: 1H-Indole-1-butanenitrile, 3-[2-(dimethylamino)ethyl]-4-(phenylmethoxy)-(500003-02-1)

Safety Data

• Hazardous Substances Data: 500003-02-1(Hazardous Substances Data)

Upstream product

• 28383-23-5 2-(4-(benzyloxy)-1H-indol-3-yl)-N,N-dimethylethan-1-amine 
• 5332-06-9 4-bromobutanenitrile 

Downstream Products

• 500003-04-3 [4-benzyloxy-3-(2-dimethylaminoethyl)indol-1-yl]butyric acid 

Relevant articles and documents

Synthesis of a psilocin hapten and a protein-hapten conjugate

Derivatives of psilocin with ω-functionalized alkyl spacers in position 1 of the indole ring were synthesized as haptens for use in a radioimmunoassay. Whereas the psilocin analogues with a 3-aminopropyl and a 4-aminobutyl moiety at the indole nitrogen decomposed during synthesis, the analogous 3-carboxypropyl psilocin derivative proved to be stable. This compound was coupled to bovine serum albumin (BSA) using the N-hydroxysuccinimide ester-mediated conjugation. The protein-hapten conjugate was characterized by matrix-assisted laser desorption ionization mass spectrometry. The mass spectrometry data indicated an average incorporation ratio of 4-5 molecules of psilocin hapten per molecule of BSA.