500789-41-3

Basic information

• Product Name: 2,4-Morpholinedicarboxylic acid, 4-(1,1-diMethylethyl) 2-Methyl ester
• Synonyms: 2,4-Morpholinedicarboxylic acid, 4-(1,1-diMethylethyl) 2-Methyl ester;4-Boc-Morpholine-2-carboxylic acid Methyl ester;4-(tert-butoxycarbonyl)-2-MethylMorpholine-2-carboxylic acid;4-(tert-Butyloxycarbonyl)morpholine-2-carboxylic acid methyl ester;tert-butyl methyl morpholine-2,4-dicarboxylate
• CAS NO: 500789-41-3
• Molecular Formula: C₁₁H₁₉NO₅
• Molecular Weight: 245.27226
• Mol File: 500789-41-3.mol
• Article Data: 13

Chemical Properties

• Boiling Point: 313.2±42.0 °C(Predicted)
• Appearance: /
• Density: 1.149±0.06 g/cm3(Predicted)
• Storage Temp.: 2-8°C
• PKA: -2.79±0.40(Predicted)
• CAS DataBase Reference: 2,4-Morpholinedicarboxylic acid, 4-(1,1-diMethylethyl) 2-Methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: 2,4-Morpholinedicarboxylic acid, 4-(1,1-diMethylethyl) 2-Methyl ester(500789-41-3)
• EPA Substance Registry System: 2,4-Morpholinedicarboxylic acid, 4-(1,1-diMethylethyl) 2-Methyl ester(500789-41-3)

Safety Data

• Hazardous Substances Data: 500789-41-3(Hazardous Substances Data)

Usage

General Description

2,4-Morpholinedicarboxylic acid, 4-(1,1-dimethylethyl) 2-methyl ester is a chemical compound with the molecular formula C12H21NO5. It is a derivative of morpholine and is commonly used as a building block in the synthesis of pharmaceuticals and other organic compounds. 2,4-Morpholinedicarboxylic acid, 4-(1,1-dimethylethyl) 2-methyl ester is a white, crystalline solid and is known for its stability and non-reactive nature. It is often used in the pharmaceutical industry as a precursor to create various medications and drugs. Additionally, it is also used in research and development for creating new chemical compounds.

Upstream product

• 189321-66-2 4-(tert-butoxycarbonyl)morpholine-2-carboxylic acid 
• 74-88-4 methyl iodide 
• 18107-18-1 diazomethyl-trimethyl-silane 
• 135782-29-5 methyl 4-benzylmorpholine-2-carboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 67-56-1 methanol 
• 75-11-6 diiodomethane 
• 1729-67-5 Methyl 2,3-dibromopropionate 
• 141-43-5 ethanolamine 

Downstream Products

• 135065-69-9 tert-butyl 2-(hydroxymethyl)morpholine-4-carboxylate 
• 135782-19-3 (RS)-2-(methoxycarbonyl)morpholine 
• 1268716-59-1 2-{3-[(Z)-hydroxyimino]-3-phenyl-propionyl}-morpholine-4-carboxylic acid tert-butyl ester 
• 1268716-60-4 2-(3-phenyl-isoxazol-5-yl)-morpholine-4-carboxylic acid tert-butyl ester 
• 1269755-24-9 4-tert-butyl 2-methyl 2-methylmorpholine-2,4-dicarboxylate 
• 1205749-71-8 4-(tert-butoxycarbonyl)-2-methylmorpholine-2-carboxylic acid 
• 1312815-11-4 4-tert-butyl 2-methyl 2-(tosyloxymethyl)morpholine-2,4-dicarboxylate 
• 1312815-12-5 4-tert-butyl 2-methyl 2-((2,4-dimethoxybenzylamino)methyl)morpholine-2,4-dicarboxylate 
• 1268716-61-5 2-(3-phenylisoxazol-5-yl)morpholine hydrochloride 
• 937063-34-8 methyl 2-morpholine carboxylate hydrochloride 
• 937060-13-4 methyl 4-{3-[(4R,6S)-8-chloro-6-(2,3-dimethoxyphenyl)-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]propanoyl}-2-morpholinecarboxylate 
• 937060-14-5 4-{3-[(4R,6S)-8-chloro-6-(2,3-dimethoxyphenyl)-4H,6H-pyrrolo[1,2-a][4,1]benzoxazepin-4-yl]propanoyl}-2-morpholinecarboxylic acid 

Relevant articles and documents

CYANO-SUBTITUTED HETEROCYCLES WITH ACTIVITY AS INHIBITORS OF USP30

The present invention relates to a class of cyano-substituted-heterocycles of Formula (I) with activity as inhibitors of deubiquitilating enzymes, in particular, ubiquitin C-terminal hydrolase 30 or ubiquitin specific peptidase 30 (USP30), having utility in a variety of therapeutic areas including cancer and conditions involving mitochondrial dysfunction. (I)

SPIROCYCLIC DEGRONIMERS FOR TARGET PROTEIN DEGRADATION

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N-ACYL PYRIDINE BIARYL COMPOUNDS AND THEIR USES

The present invention provides a compound of general formula:wherein Z2-Z6 include one or two nitrogen atoms as described herein, including pharmaceutically acceptable salts, enantiomers, stereoisomers, rotamers, tautomers, diastereomers, or racemates thereof. These compounds inhibit the activity of CDK9 and are thus useful as pharmaceuticals. Also provided are methods of treating a disease or condition mediated by CDK9 using the compounds of Formula I and isomers thereof, and pharmaceutical compositions comprising such compounds.