500878-72-8

Basic information

• Product Name: 1-Pentanol, 5-[(4-methoxyphenyl)diphenylmethoxy]-
• CAS NO: 500878-72-8
• Molecular Formula: C25H28O3
• Molecular Weight: 376.496
• Mol File: 500878-72-8.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-Pentanol, 5-[(4-methoxyphenyl)diphenylmethoxy]-(CAS DataBase Reference)
• NIST Chemistry Reference: 1-Pentanol, 5-[(4-methoxyphenyl)diphenylmethoxy]-(500878-72-8)
• EPA Substance Registry System: 1-Pentanol, 5-[(4-methoxyphenyl)diphenylmethoxy]-(500878-72-8)

Safety Data

• Hazardous Substances Data: 500878-72-8(Hazardous Substances Data)

Upstream product

• 1220688-65-2 C₄₆H₄₇NO₃ 
• 111-29-5 1 ,5-pentanediol 
• 14470-28-1 mono-4-methoxytrityl chloride 

Downstream Products

• 111-29-5 1 ,5-pentanediol 
• 500878-76-2 tert-butyl 3-{[4-(5-hydroxypentyloxy)benzyl]amino}propanoate 
• 500878-74-0 4-[5-(4-methoxytrityloxy)pentyloxy]benzaldehyde 

Relevant articles and documents

Facilitated photochemical cleavage of benzylic C-O bond. Application to photolabile hydroxyl-protecting group design

A new photolabile hydroxyl-protecting group has been developed by introducing a dimethylamino group to the meta position of an aromatic ring of the traditional trityl (Tr) protecting group. The Royal Society of Chemistry 2010.

Synthesis of spirobicyclic peptides on a solid support

The spirobicyclic peptides 2-6 were synthesized as stereoisomeric pairs using an orthogonally protected bis(aminomethyl)malonic acid building block 1 as the branching unit. Peptide 2 was synthesized by two methods. Either the chain assembly and first cyclization were carried out on a Wang resin, and the second cyclization in solution (Scheme 1), or the whole synthesis was performed on a solid-supported backbone amide linker derived from 4-alkoxybenzaldehyde (Scheme 3). The applicability of the latter method was further evaluated by synthesis of four additional spirobicyclic peptides 3-6.