501037-05-4

Basic information

• Product Name: 2-Pentanone, 1,1,1-trifluoro-5-(phenylmethoxy)-, O-(phenylmethyl)oxime
• CAS NO: 501037-05-4
• Molecular Formula: C19H20F3NO2
• Molecular Weight: 351.369
• Mol File: 501037-05-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 2-Pentanone, 1,1,1-trifluoro-5-(phenylmethoxy)-, O-(phenylmethyl)oxime(CAS DataBase Reference)
• NIST Chemistry Reference: 2-Pentanone, 1,1,1-trifluoro-5-(phenylmethoxy)-, O-(phenylmethyl)oxime(501037-05-4)
• EPA Substance Registry System: 2-Pentanone, 1,1,1-trifluoro-5-(phenylmethoxy)-, O-(phenylmethyl)oxime(501037-05-4)

Safety Data

• Hazardous Substances Data: 501037-05-4(Hazardous Substances Data)

Upstream product

• 501036-99-3 N-benzyloxy-2,2,2-trifluoro-thioacetimidic acid phenyl ester 
• 501036-98-2 N-(benzyloxy)-2,2,2-trifluoroacetimidoyl chloride 
• 622-33-3 N-benzyloxyamine 
• 5375-00-8 3-benzyloxypropyl iodide 
• 501037-00-9 1-benzenesulfonyl-2,2,2-trifluoro-ethanone O-benzyl-oxime 

Downstream Products

• 501037-12-3 4-benzyloxy-1-trifluoromethyl-butylamine 

Relevant articles and documents

Radical-mediated synthesis of trifluoroethyl amines and trifluoromethyl ketones from alkyl iodides

Radical reaction of alkyl iodides with trifluoromethyl phenylsulfonyl oxime ether 10 and hexamethylditin at 300 nm in benzene afforded the corresponding trifluoromethyl oxime ethers 11 in high yields, which were reduced into the 2,2,2-trifluoroethyl amines with lithium aluminium hydride. The trifluoroethyl amines could be converted into the corresponding trifluoromethyl ketones by treatment with NBS and DBU.