501346-95-8

Basic information

• Product Name: 5-[N-benzyl-N-(2-iodophenyl)amino]-2-pentanone ethylene acetal
• Synonyms: 5-[N-benzyl-N-(2-iodophenyl)amino]-2-pentanone ethylene acetal
• CAS NO: 501346-95-8
• Molecular Weight: 437.321
• Mol File: 501346-95-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 5-[N-benzyl-N-(2-iodophenyl)amino]-2-pentanone ethylene acetal(CAS DataBase Reference)
• NIST Chemistry Reference: 5-[N-benzyl-N-(2-iodophenyl)amino]-2-pentanone ethylene acetal(501346-95-8)
• EPA Substance Registry System: 5-[N-benzyl-N-(2-iodophenyl)amino]-2-pentanone ethylene acetal(501346-95-8)

Safety Data

• Hazardous Substances Data: 501346-95-8(Hazardous Substances Data)

Upstream product

• 100-39-0 benzyl bromide 
• 615-43-0 2-iodophenylamine 
• 24108-29-0 3-(2-methyl-[1,3]dioxolan-2-yl)-propionaldehyde 

Downstream Products

• 390432-42-5 5-[N-benzyl-N-(2-iodophenyl)amino]-2-pentanone 

Relevant articles and documents

Intramolecular Pd-mediated processes of amino-tethered aryl halides and ketones: Insight into the ketone α-arylation and carbonyl-addition dichotomy. A new class of four-membered azapalladacycles

An exploration of the scope and limitations of Pd(O)-catalyzed intramolecular coupling reactions of amino-tethered aryl halides and ketones has been conducted. Two different and competitive reaction pathways starting from ω-(2-haloanilino) alkanones, enolate arylation and addition to the carbonyl group, have been observed, while ω-(2-halobenzylamino) alkanones exclusively underwent the enolate arylation process. The dichotomy between ketone α-arylation and carbonyl-addition in the reactions of ω-(2-haloanilino) alkanones has been rationalized by the intermediacy of unprecedented four-membered azapalladacycles, from which X-ray data and chemical behavior are reported.