501381-03-9

Basic information

• Product Name: (R(P))-PH(Me)(Ph)(BH₃)
• CAS NO: 501381-03-9
• Molecular Weight: 137.957
• Mol File: 501381-03-9.mol
• Article Data: 9

Chemical Properties

• CAS DataBase Reference: (R(P))-PH(Me)(Ph)(BH₃)(CAS DataBase Reference)
• NIST Chemistry Reference: (R(P))-PH(Me)(Ph)(BH₃)(501381-03-9)
• EPA Substance Registry System: (R(P))-PH(Me)(Ph)(BH₃)(501381-03-9)

Safety Data

• Hazardous Substances Data: 501381-03-9(Hazardous Substances Data)

Upstream product

• 6372-48-1 methylphenylphosphine 
• 16940-66-2 sodium tetrahydroborate 
• 1079-66-9 chloro-diphenylphosphine 
• 41593-58-2 diphenylphosphineborane 
• 54067-17-3 diphenylmethylphosphine-borane complex 
• 644-97-3 Dichlorophenylphosphine 
• 6389-79-3 methyl methylphenylphosphinate 
• 19315-13-0 methyl(phenyl)phosphineoxide 
• 1354049-94-7 C₇H₈ClP*ClH 
• 2946-61-4 phenylphosphonous acid dimethyl ester 
• 6996-29-8 phenylphosphine-borane 
• 74-88-4 methyl iodide 
• 119-61-9 benzophenone 

Downstream Products

• 31277-98-2 bis[1,2-bis(diphenylphosphino)ethane]palladium⁽⁰⁾ 
• 129212-59-5 (R(P))-(o-anisyl)(methyl)(phenyl)phosphine-P-borane 
• 19998-21-1 [PdI₂(1,2-bis(diphenylphosphino)ethane)] 
• 882176-76-3 1,3-bis((methylphenylphosphino-borane)methyl)benzene 
• 1172134-69-8 C₁₅H₁₈BN₂O₃P 
• 1172134-72-3 C₂₀H₂₂BO₂P 
• 1172134-67-6 C₂₀H₂₈BO₂P 
• 1172134-71-2 C₂₄H₃₀B₂O₂P₂ 
• 1172134-60-9 C₁₅H₁₈BOP 
• 1172134-62-1 C₁₆H₂₀BO₂P 
• 377764-13-1 1-phenylphospholane-borane 
• 1256259-55-8 H₃BP(CH₃)(C₆H₅)C₆H₉ 

Relevant articles and documents

l-Menthol-Assisted Synthesis of P-Stereogenic Phosphinous Acid Amides and Phosphine-Boranes

Diastereomerically pure phenylphosphonous acid-borane l-menthyl ester N,N-diethylamide was obtained through the fractional crystallization of a diastereomeric mixture of compounds synthesized from PhPCl2, l-menthol, diethylamine, and BH3·THF. Treatment of racemic or diastereomerically pure phenylphosphonous acid-borane derivatives with sodium in liquid ammonia followed by the addition of an electrophile led to the formation of phosphinous acid-amides. Surprisingly, these compounds undergo preferential P–N bond cleavage under Birch reduction conditions.

In situ dearomatisation/alkylation of arylphosphane derivatives

The dearomatisation of aryldialkylphosphane-boranes and aryldialkylphosphane oxides under Birch reduction conditions, followed by treatment with reactive alkyl halides, provides the corresponding α-functionalised (cyclohexa-1,4-dien-3-yl)phosphane derivatives. This reaction offers a method of choice for the synthesis of bulky (cyclohexadienyl)phosphanes.

7-Phosphanorbornenium borohydrides: A powerful route to functional secondary phosphine-borane complexes

The reaction of phosphanorbornenium triflates with sodium borohydride gives the secondary phosphine-borane complexes by reductive cleavage of the two P-C bonds of the bridge. This route is compatible with functionalities such as Cl, CN, CO2Et, and Th.