501921-80-8

Basic information

• Product Name: 1H-Indole-3-acetamide, N-(4-chloro-3-methyl-5-isothiazolyl)-1-[(4-chlorophenyl)methyl]-a-oxo-
• CAS NO: 501921-80-8
• Molecular Formula: C21H15Cl2N3O2S
• Molecular Weight: 444.341
• Mol File: 501921-80-8.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1H-Indole-3-acetamide, N-(4-chloro-3-methyl-5-isothiazolyl)-1-[(4-chlorophenyl)methyl]-a-oxo-(CAS DataBase Reference)
• NIST Chemistry Reference: 1H-Indole-3-acetamide, N-(4-chloro-3-methyl-5-isothiazolyl)-1-[(4-chlorophenyl)methyl]-a-oxo-(501921-80-8)
• EPA Substance Registry System: 1H-Indole-3-acetamide, N-(4-chloro-3-methyl-5-isothiazolyl)-1-[(4-chlorophenyl)methyl]-a-oxo-(501921-80-8)

Safety Data

• Hazardous Substances Data: 501921-80-8(Hazardous Substances Data)

Upstream product

• 96841-04-2 5-amino-4-chloro-3-methyl-isothiazole 
• 348111-64-8 2-[1-(4-chlorobenzyl)-1H-indol-3-yl]-2-oxoacetyl chloride 

Relevant articles and documents

Indole- and indolizine-glyoxylamides displaying cytotoxicity against multidrug resistant cancer cell lines

We report herein the SAR studies of a series of indole- and indolizine-glyoxylamides that demonstrate substantial in vitro anti-proliferative activities against cancer cell lines, including multidrug resistance (MDR) phenotypes. The in vitro cytotoxic effects have been demonstrated across a wide array of tumor types of various origins (e.g., breast, colon, uterine).