502159-03-7

Basic information

• Product Name: Pyridine, 2-[[2-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]thio]-
• CAS NO: 502159-03-7
• Molecular Formula: C16H17NO2S
• Molecular Weight: 287.382
• Mol File: 502159-03-7.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: Pyridine, 2-[[2-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]thio]-(CAS DataBase Reference)
• NIST Chemistry Reference: Pyridine, 2-[[2-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]thio]-(502159-03-7)
• EPA Substance Registry System: Pyridine, 2-[[2-[(tetrahydro-2H-pyran-2-yl)oxy]phenyl]thio]-(502159-03-7)

Safety Data

• Hazardous Substances Data: 502159-03-7(Hazardous Substances Data)

Upstream product

• 108-95-2 phenol 
• 110-87-2 3,4-dihydro-2H-pyran 
• 4203-50-3 2-phenoxytetrahydropyran 
• 2127-03-9 2,2'-dipyridyldisulphide 

Downstream Products

• 502159-05-9 2-(pyridin-2-yl-sulfanyl)-phenol 

Relevant articles and documents

Identification of Suitable Ligands for a Transition Metal-Catalyzed Reaction: Screening of a Modular Ligand Library in the Enantioselective Hydroboration of Styrene

Based on a general modular synthetic scheme, a variety of chiral bidentate P/P-, P/S-, P/N-, and P/Se-ligands is accessible in an efficient divergent manner starting from phenol or naphthol derived backbone systems. A library of 20 selected ligands was tested in the Rh-catalyzed asymmetric hydroboration of styrene to give 1-phenylethanol in up to 91% ee after oxidative work-up. It was demonstrated that small variations of the ligand structures lead to pronounced, unpredictable differences in the performance of the in situ generated rhodium complexes. The modular approach should be applicable for the identification and optimization of suitable ligands for other transition metal-catalyzed transformations with comparably low effort.