502649-32-3 Usage
Description
1-Boc-3-isopropyl-piperazine is an organic compound that serves as a valuable building block in the synthesis of various pharmaceuticals and bioactive molecules. It is characterized by its unique structural features, which include a piperazine core with an isopropyl group at the 3-position and a tert-butoxycarbonyl (Boc) protecting group at the 1-position. 1-Boc-3-isopropyl-piperazine is known for its stability and reactivity, making it a versatile component in the development of new drugs and therapeutic agents.
Uses
Used in Pharmaceutical Industry:
1-Boc-3-isopropyl-piperazine is used as a key intermediate for the synthesis of benzoisothiazoles, which are known as KRAS G12C inhibitors. These inhibitors play a crucial role in the development of targeted cancer therapies, as they help to block the activity of the KRAS protein, a common mutation found in various types of cancer. By inhibiting the KRAS protein, these benzoisothiazoles can potentially slow down or stop the growth of cancer cells, offering a promising avenue for cancer treatment.
Check Digit Verification of cas no
The CAS Registry Mumber 502649-32-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 5,0,2,6,4 and 9 respectively; the second part has 2 digits, 3 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 502649-32:
(8*5)+(7*0)+(6*2)+(5*6)+(4*4)+(3*9)+(2*3)+(1*2)=133
133 % 10 = 3
So 502649-32-3 is a valid CAS Registry Number.
InChI:InChI=1/C12H24N2O2/c1-9(2)10-8-14(7-6-13-10)11(15)16-12(3,4)5/h9-10,13H,6-8H2,1-5H3
502649-32-3Relevant articles and documents
PIPERAZINE AND HOMOPIPERAZINE COMPOUNDS
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, (2008/06/13)
Compounds are provided having a piperazine or homopiperazine ring which are useful in the treatment of thrombosis.
