50271-62-0

Basic information

• Product Name: α-D-Manp-(1->2)-α-D-Manp
• Synonyms: α-D-Manp-(1->2)-α-D-Manp
• CAS NO: 50271-62-0
• Molecular Weight: 342.3
• Mol File: 50271-62-0.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: α-D-Manp-(1->2)-α-D-Manp(CAS DataBase Reference)
• NIST Chemistry Reference: α-D-Manp-(1->2)-α-D-Manp(50271-62-0)
• EPA Substance Registry System: α-D-Manp-(1->2)-α-D-Manp(50271-62-0)

Safety Data

• Hazardous Substances Data: 50271-62-0(Hazardous Substances Data)

Upstream product

• 530-26-7 D-Mannose 
• 991-43-5 guanosine 5'-diphospho-D-mannose 

Relevant articles and documents

Large Scale Production of Recombinant α-1,2-Mannosyltransferase from E. coli for the Study of Acceptor Specificity and Use of the Recombinant Whole Cells in Synthesis

We report the first large scale heterologous expression of a recombinant yeast α-1,2-mannosyltransferase in E. coli.The enzyme was isolated from 10-L and 50-L fermentations, purified and used for mannosylation reactions.The specificity of the recombinant enzyme was extensively studied by using mannose derivatives, oligosaccharides, and analogs as acceptors, and the results show that the enzyme exhibits high activities toward ManOMe and disaccharides connected by an α-1,2-mannosidic linkage.The recombinant E. coli cells were also used as a catalyst for glycosylation reaction, and mannosylation of saccharides and glycopeptides proceeded in moderate to good yields.