502841-31-8Relevant articles and documents
Synthesis of pyrrolidine based natural or unnatural product derivatives (1): Application of efficient asymmetric induction of C-2 position in polysubstituted pyrrolidines
Jeong, Hyung Jae,Lee, Ju Man,Kim, Min Kyu,Lee, Sang-Gyeong
, p. 1019 - 1024 (2007/10/03)
A novel method for synthesis of polysubstituted pyrrolidines, which possess a C-2 stereocenter, was developed. The strategy involves Grignard addition to the succinimide, derived from L-tartaric acid, followed by stereocontrolled triethylsilane promoted reduction of the resulting cyclic amidols.